909947
3-Azido-L-alanine hydrochloride
≥95%
别名:
(S)-2-Amino-3-azidopropanoic acid hydrochloride, 3-Azido-L-alanine HCl, 3-Azido-L-alanine hydrochloride, H-L-Ala(N3)-OH*HCl, H-L-Aza-OH*HCl, H-L-Dap(N3)-OH*HCl
方案
≥95%
表单
solid
反应适用性
reaction type: solution phase peptide synthesis
存货情况
available only in USA
储存温度
2-8°C
应用
The in vivo incorporation of clickable unnatural amino acids such as 3-Azido-L-alanine with unique reactivity at a defined postition is used for functionalization of proteins. The azide functionalities in the protein can then be modified with almost any alkyne bearing molecule by Cu(I)-catalyzed azide-alkyne cycloaddition (CuAAC). Copper-free alternatives with strained internal alkynes are also available (SPAAC). Some examples enabled with this technique are protein PEGylation, masking with sugars, and the attachment to antibodies.
警示用语:
Danger
危险声明
危险分类
Self-react. C
储存分类代码
5.2 - Organic peroxides and self-reacting hazardous materials
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
此项目有
Kristi L Kiick et al.
Proceedings of the National Academy of Sciences of the United States of America, 99(1), 19-24 (2001-12-26)
The introduction of chemically unique groups into proteins by means of non-natural amino acids has numerous applications in protein engineering and functional studies. One method to achieve this involves the utilization of a non-natural amino acid by the cell's native
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