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Merck
CN

91594

Supelco

N1-Acetylsulfamethoxazole

analytical standard

别名:

N-[(4-Aminophenyl)sulfonyl]-N-(5-methyl-3-isoxazolyl)acetamide, N1-Acetyl-N1-(5-methyl-3-isoxazolyl)sulfanilamide

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关于此项目

经验公式(希尔记法):
C12H13N3O4S
化学文摘社编号:
分子量:
295.31
Beilstein:
893012
EC 号:
UNSPSC代码:
41116107
NACRES:
NA.24
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等级

analytical standard

质量水平

方案

≥95.0% (HPLC)

保质期

limited shelf life, expiry date on the label

技术

HPLC: suitable
gas chromatography (GC): suitable

杂质

≤1.0% water

应用

pharmaceutical

包装形式

neat

储存温度

2-8°C

SMILES字符串

NC1=CC=C(S(=O)(N(C2=NOC(C)=C2)C(C)=O)=O)C=C1

InChI

1S/C12H13N3O4S/c1-8-7-12(14-19-8)15(9(2)16)20(17,18)11-5-3-10(13)4-6-11/h3-7H,13H2,1-2H3

InChI key

WOTJLXVSBKKTTH-UHFFFAOYSA-N

一般描述

N1-Acetylsulfamethoxazole is a metabolite of the bacteriostatic antibiotic sulfamethoxazole, which is typically utilized for the treatment of various diseases in humans as well as animals.

应用

N1-Acetylsulfamethoxazole may be used as an analytical standard for the determination of the analyte in soil and plant samples by liquid chromatography coupled to tandem mass spectrometry (LC-MS/MS).

象形图

Exclamation mark

警示用语:

Warning

危险分类

Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

靶器官

Respiratory system

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Renato F Dantas et al.
Journal of hazardous materials, 150(3), 790-794 (2007-06-19)
Sulfamethoxazole (SMX) is a bacteriostatic antibiotic largely used for diverse types of illness. Its widely use in humans and even in animals releases unmetabolized and active metabolites that have a strong potential in terms of effect in organisms. In this
Sonia Blasioli et al.
Journal of colloid and interface science, 419, 148-159 (2014-02-05)
Sulfonamide antibiotics are persistent pollutants present in surface and subsurface waters in both agricultural and urban environments. Sulfonamides are of particular concern in the environment because they are known to induce high levels of bacterial resistance. Adsorption of sulfamethoxazole sulfonamide
Uptake, translocation and transformation of three pharmaceuticals in green pea plants
Klement A, et al.
Journal of Hydrology and Hydromechanics, 68(1) (2020)

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