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经验公式(希尔记法):
C25H24O12
化学文摘社编号:
分子量:
516.45
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
85151701
MDL number:
InChI key
YDDUMTOHNYZQPO-RVXRWRFUSA-N
SMILES string
O[C@@H]1C[C@](C[C@@H](OC(=O)\C=C\c2ccc(O)c(O)c2)[C@H]1O)(OC(=O)\C=C\c3ccc(O)c(O)c3)C(O)=O
InChI
1S/C25H24O12/c26-15-5-1-13(9-17(15)28)3-7-21(31)36-20-12-25(24(34)35,11-19(30)23(20)33)37-22(32)8-4-14-2-6-16(27)18(29)10-14/h1-10,19-20,23,26-30,33H,11-12H2,(H,34,35)/b7-3+,8-4+/t19-,20-,23+,25-/m1/s1
grade
analytical standard
assay
≥98.0% (HPLC)
shelf life
limited shelf life, expiry date on the label
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
impurities
≤10.0% water
application(s)
food and beverages
format
neat
storage temp.
2-8°C
Quality Level
General description
洋蓟素是洋蓟植物的活性成分,具有利胆和降胆固醇活性。它还广泛用于草药方剂,用于治疗肝病中的特殊适应症。
Application
有关合适仪器技术的更多信息,请参考产品′s分析证书。如需进一步支持,请联系技术服务。
洋蓟素可作为分析标准品,通过高效液相色谱技术对血浆样品中的分析物进行定量分析。
Biochem/physiol Actions
在朝鲜蓟中发现的酚类化合物。抗氧化和利胆作用。潜在的免疫抑制剂。
Packaging
无底玻璃瓶。内容物在插入式融锥内。
Other Notes
这种化合物常见于以下属的植物中:山金车
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Validated HPLC method for cynarin determination in biological samples
Alonso RM, et al.
Acta Acad. Med. Sin., 25(2), 267-267 (2006)
Esra Erikel et al.
Journal of ethnopharmacology, 237, 171-181 (2019-03-21)
Cynarin is an artichoke phytochemical that possesses a variety of pharmacological features including free-radical scavenging and antioxidant activity. The origin of artichoke species appears to be Mediterranean region. Two of these species, globe artichoke (Cynara cardunculus var. scolymus L.) and
Guo-Chung Dong et al.
Journal of medicinal chemistry, 49(6), 1845-1854 (2006-03-17)
AFTIR (after flowing through immobilized receptor) is a novel method for screening herbal extracts for pharmaceutical properties. Using AFTIR, we identified Cynarin in Echinacea purpurea by its selective binding to chip immobilized CD28, a receptor of T-cells, which is instrumental
Yi Wang et al.
Bioorganic & medicinal chemistry letters, 21(23), 7064-7067 (2011-10-22)
The complex and highly impermeable cell wall of Mycobacterium tuberculosis (Mtb) is largely responsible for the ability of the mycobacterium to resist the action of chemical therapeutics. An L-rhamnosyl residue, which occupies an important anchoring position in the Mtb cell
Bianca Sperl et al.
Bioorganic & medicinal chemistry letters, 19(12), 3305-3309 (2009-05-12)
In this Letter, we report the natural products salvianolic acid A, salvianolic acid B, and caftaric acid as inhibitors of the protein-protein interactions mediated by the SH2 domains of the Src-family kinases Src and Lck, two established disease targets. Moreover
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