91823
吉非罗齐
analytical standard
别名:
2,2-二甲基-5-(2,5-二甲基苯氧基)戊酸, 2,2-二甲基-5-(2,5-二甲苯氧基)戊酸, 5-(2,5-二甲基苯氧基)-2,2-二甲基戊酸
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关于此项目
经验公式（希尔记法）:
C15H22O3
化学文摘社编号:
分子量:
250.33
UNSPSC Code:
41116107
PubChem Substance ID:
EC Number:
247-280-2
MDL number:
InChI key
HEMJJKBWTPKOJG-UHFFFAOYSA-N
InChI
1S/C15H22O3/c1-11-6-7-12(2)13(10-11)18-9-5-8-15(3,4)14(16)17/h6-7,10H,5,8-9H2,1-4H3,(H,16,17)
SMILES string
Cc1ccc(C)c(OCCCC(C)(C)C(O)=O)c1
grade
analytical standard
assay
≥98.5% (GC)
shelf life
limited shelf life, expiry date on the label
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
impurities
≤0.5% water
application(s)
forensics and toxicology
pharmaceutical (small molecule)
format
neat
Quality Level
Gene Information
human ... PPARA(5465)
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P A Todd et al.
Drugs, 36(3), 314-339 (1988-09-01)
Gemfibrozil is a lipid-regulating agent which is generically classified as a fibric acid derivative, but which exhibits different pharmacological effects from other such drugs. Published data indicate that in patients with all types of dyslipidaemia (except type I) gemfibrozil 800
P Zimetbaum et al.
Journal of clinical pharmacology, 31(1), 25-37 (1991-01-01)
Fibric acid derivatives (FADs) are a class of drugs that have been shown to reduce the production of very low-density lipoprotein (VLDL) while enhancing VLDL clearance due to the stimulation of lipoprotein lipase activity. The drugs can reduce plasma triglyceride
G J Magarian et al.
Archives of internal medicine, 151(9), 1873-1874 (1991-09-01)
Drug-induced myopathy has been reported with use of lovastatin, nicotinic acid, and clofibrate. A particularly severe form, often accompanied by rhabdomyolysis, has been reported with the use of lovastatin and gemfibrozil; however, as far as we know, no case has
C M Spencer et al.
Drugs, 51(6), 982-1018 (1996-06-01)
Gemfibrozil improves lipid and apolipoprotein profiles, particularly very low density lipoprotein (VLDL) triglyceride and high density lipoprotein (HDL) cholesterol levels, in patients with dyslipidaemia when administered at a total daily dose of 900 or 1200 mg. As demonstrated by the
Wendy H Krkosek et al.
Water environment research : a research publication of the Water Environment Federation, 86(7), 654-662 (2014-08-13)
Aqueous chlorination kinetics of the lipid regulator gemfibrozil and the formation of reaction products were investigated in deionized water over the pH range 3 to 9, and in two wastewater matrices. Chlorine oxidation of gemfibrozil was found to be highly
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