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Merck
CN

92301

单核细胞增多性李斯特菌选择性添加剂 I

suitable for microbiology

别名:

多粘菌素 B 硫酸盐, 单核细胞增生李斯特菌选择性添加剂 I

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选择尺寸

关于此项目

经验公式（希尔记法）:
C55H96N16O13 · 2H2SO4
化学文摘社编号:
1405-20-5
分子量:
1385.61
UNSPSC Code:
41106200
NACRES:
NA.85
EC Number:
215-774-7
MDL number:
MFCD00131991

主要文件

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InChI key

HNDFYNOVSOOGDU-UHFFFAOYSA-N

InChI

1S/C48H82N16O13.H2O4S/c1-27(2)24-37-47(76)59-32(11-19-52)41(70)56-31(10-18-51)43(72)61-35(14-22-65)39(68)54-21-13-34(45(74)57-33(12-20-53)44(73)64-38(48(77)63-37)25-28-6-4-3-5-7-28)60-42(71)30(9-17-50)58-46(75)36(15-23-66)62-40(69)29(8-16-49)55-26-67;1-5(2,3)4/h3-7,26-27,29-38,65-66H,8-25,49-53H2,1-2H3,(H,54,68)(H,55,67)(H,56,70)(H,57,74)(H,58,75)(H,59,76)(H,60,71)(H,61,72)(H,62,69)(H,63,77)(H,64,73);(H2,1,2,3,4)

SMILES string

O=C(C(NC(C(CCN)NC(CCCCC(C)CC)=O)=O)C(C)O)NC(CCN)C(NC(CCNC(C(NC(C(NC(C(CCN)N1)=O)CCN)=O)C(O)C)=O)C(NC(CCN)C(NC(CC2=CC=CC=C2)C(NC(CC(C)C)C1=O)=O)=O)=O)=O.O=S(O)(O)=O

sterility

sterile

form

powder

shelf life

limited shelf life, expiry date on the label

antibiotic activity spectrum

Gram-negative bacteria, Gram-positive bacteria, fungi

application(s)

environmental
food and beverages, microbiology

mode of action

cell membrane | interferes

storage temp.

2-8°C

suitability

Listeria spp.

Quality Level

100

General description

由 ISO 委员会建议用于分离李斯特菌的选择性添加剂。
Chemical structure: peptide

Application

for the isolation of Listeria species

Biochem/physiol Actions

作用机制：多粘菌素B硫酸盐结合到细菌脂多糖的脂质部分†上，通过诱导足够大的孔来破坏细胞质膜，使核苷酸泄漏到细菌的细胞壁中。 这可破环细胞质膜的半透性。

抗菌谱：对大多数革兰氏阴性杆菌，包括 大肠杆菌 ，真菌和革兰氏阳性菌都有杀菌作用。

Other Notes

（每瓶，足够用于 500mL 培养基）
硫酸多粘菌素 B 38350IU

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302

Hazard Classifications

Acute Tox. 4 Oral

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
BCCC1960
BCCB2658
BCBV0595
BCBT4252
BCBT0349

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Nahoko Sato et al.
Chest, 143(4), 1146-1150 (2013-04-03)
Amiodarone pulmonary toxicity (APT) is the most serious side effect of amiodarone. Although severe APT, such as ARDS, is rare, mortality of severe APT is high. Polymyxin B-immobilized fiber column direct hemoperfusion (PMX-DHP) is a medical device that reduces blood
Jung-Whan Chon et al.
International journal of food microbiology, 162(3), 308-310 (2013-03-12)
A new Campylobacter-selective enrichment broth supplemented with bacteriological charcoal and a high concentration of polymyxin B was developed (charcoal-cefoperazone-polymyxin B-deoxycholate broth; CCPD broth). We compared the ability of CCPD broth to detect Campylobacter jejuni and Campylobacter coli in chicken carcass
Kensuke Nakamura et al.
The American journal of emergency medicine, 31(5), 893-893 (2013-02-13)
Septic patients often have low cardiac output. Some of them present severe cardiac dysfunction such as septic cardiomyopathy. However, no well-known and effective treatment for septic cardiomyopathy exists. The effect of endotoxin adsorption by polymyxin B–immobilized fiber column–direct hemoperfusion (PMX-DHP)
A Bonura et al.
Allergy, 68(3), 297-303 (2013-01-22)
The major allergens in Parietaria pollen, Par j 1 and Par j 2, have been identified as lipid transfer proteins. The family of the Par j 1 allergens is composed of two isoforms, which differ by the presence of a
Lee Sun New et al.
Analytical and bioanalytical chemistry, 405(4), 1407-1415 (2012-11-28)
With increasing multidrug resistance coupled to a poor development pipeline, clinicians are exploring antimicrobial combinations to improve treatment outcomes. In vitro hollow-fiber infection model (HFIM) is employed to simulate human in vivo drug clearance and investigate pharmacodynamic synergism of antibiotics.
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实验方案

李斯特菌：不可不防

近年来，李斯特菌病被定为重大的公共健康问题。这种病的主要感染对象是老年人、孕妇、新生儿和免疫功能低下者。

Understanding Listeria: Guide to Listeria Monocytogenes and Its Impact on Food Safety

Ensure food safety with our robust Listeria monocytogenes testing methods, including biochemical tests, chromogenic media, and rapid detection methods.

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