96045
2-(Hydroxymethyl)butyric acid sodium salt
analytical standard
别名:
2-Ethyl-3-hydroxypropionic acid, 2-Ethylhydracrylic acid sodium salt, Sodium 2-(hydroxymethyl)butyrate
SMILES string
O=C(O[Na])C(CO)CC
grade
analytical standard
assay
≥95.0% (GC)
shelf life
limited shelf life, expiry date on the label
application(s)
clinical testing
format
neat
storage temp.
2-8°C
General description
2-(Hydroxymethyl)butyric acid sodium salt is a urine organic acid, reportedly found in increased concentrations in primary hyperoxaluria type 2 patients.
Application
2-(Hydroxymethyl)butyric acid sodium salt may be used as an analytical standard for the determination of the analyte in the following:
- Cerebrospinal fluid using two-dimensional gas chromatography coupled to time-of-flight mass spectrometry (GC × GC–TOFMS).
- Body fluids using gas chromatography-mass spectrometry (GC-MS).
Other Notes
Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Use of a thick-film capillary column for the analysis of organic acids in body fluids
Meier-Augenstein W, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 615(1), 127-135 (1993)
Characterization of cerebrospinal fluid by comprehensive two-dimensional gas chromatography coupled to time-of-flight mass spectrometry
Hartonen M, et al.
Journal of Chromatography A, 1293(2), 142-149 (2013)
Malonic aciduria in Maltese dogs: normal methylmalonic acid concentrations and malonyl?CoA decarboxylase activity in fibroblasts
O?Brien PD, et al.
Journal of inherited metabolic disease, 22(8), 883-890 (1999)
Severe child form of primary hyperoxaluria type 2-a case report revealing consequence of GRHPR deficiency on metabolism
Konkolova J, et al.
BMC Medical Genetics, 18(1), 59-59 (2017)
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