97582
乙酰唑胺
analytical standard
别名:
5-乙酰胺基-1,3,4-噻二唑-2-磺酰胺, N-（5-[氨基磺酰基]-1,3,4-噻二唑-2-基）乙酰胺, N-（5-氨磺酰基-1,3,4-噻二唑-2-基）乙酰胺
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关于此项目
经验公式（希尔记法）:
C4H6N4O3S2
化学文摘社编号:
分子量:
222.25
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
EC Number:
200-440-5
MDL number:
InChI key
BZKPWHYZMXOIDC-UHFFFAOYSA-N
InChI
1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9)
SMILES string
CC(=O)Nc1nnc(s1)S(N)(=O)=O
grade
analytical standard
assay
≥99.0% (HPLC)
shelf life
limited shelf life, expiry date on the label
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
impurities
≤1.0% water
application(s)
forensics and toxicology
veterinary
format
neat
Quality Level
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Application
碳酸酐酶抑制剂；增加脑血流量。
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Biochem/physiol Actions
通过与水通道蛋白相互作用抑制膜的水渗透性
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
监管及禁止进口产品
此项目有
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Nocturnal periodic breathing occurs more frequently in men than in women with various clinical and pathophysiologic conditions. The mechanisms accounting for this sex-related difference are not completely understood. Acetazolamide effectively counteracts nocturnal periodic breathing, but it has been investigated almost
Sinan Bilginer et al.
Journal of enzyme inhibition and medicinal chemistry, 29(4), 495-499 (2013-07-03)
A series of phenols incorporating tertiary amine and trans-pyridylethenyl-carbonyl moieties were assayed as inhibitors of the β-carbonic anhydrase (CA, EC 4.2.1.1) from Saccharomyces cerevisiae, ScCA. One of these compounds was a low nanomolar ScCA inhibitor, whereas the remaining ones inhibited
Deborah S Schumacher et al.
Chest, 146(5), 1226-1236 (2014-07-06)
Sleep-disturbed breathing (SDB) is common in patients with precapillary pulmonary hypertension (PH). Nocturnal oxygen therapy (NOT) and acetazolamide improve SDB in patients with PH, and NOT improves exercise capacity. We investigated the effect of NOT and acetazolamide on nocturnal cardiac
Jyotsana Singh et al.
Drug development and industrial pharmacy, 40(9), 1223-1232 (2013-07-11)
The objective of research was to develop a novel pH-triggered polymeric nanoparticulate in situ gel (NP-ISG) for ophthalmic delivery of acetazolamide (ACZ) to enhance the conjunctival permeation and precorneal residence time of the formulation by overcoming the limitations of protective
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Cutaneous and ocular toxicology, 33(2), 115-119 (2013-07-12)
The aim of this study was to evaluate the differences, in terms of visual outcome and treatment needs, between smokers and non-smokers central serous chorioretinopathy (CSCR) patients. The files of 252 patients diagnosed with CSCR who had presented to the
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