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关于此项目
经验公式(希尔记法):
C21H18ClNO6
化学文摘社编号:
分子量:
415.82
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
EC Number:
258-403-4
MDL number:
grade
analytical standard
Quality Level
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
application(s)
forensics and toxicology
pharmaceutical (small molecule)
veterinary
format
neat
SMILES string
COc1ccc2n(c(C)c(CC(=O)OCC(O)=O)c2c1)C(=O)c3ccc(Cl)cc3
InChI
1S/C21H18ClNO6/c1-12-16(10-20(26)29-11-19(24)25)17-9-15(28-2)7-8-18(17)23(12)21(27)13-3-5-14(22)6-4-13/h3-9H,10-11H2,1-2H3,(H,24,25)
InChI key
FSQKKOOTNAMONP-UHFFFAOYSA-N
Gene Information
human ... PTGS1(5742), PTGS2(5743)
Application
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Biochem/physiol Actions
该非甾体抗炎药 (NSAID) 专门增强蒽环类药(阿霉素、柔红霉素和 epirubium)的细胞毒性。避免 MRP 介导的多药耐药性。
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 1 Inhalation - Acute Tox. 2 Dermal - Acute Tox. 2 Oral
存储类别
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
wgk
WGK 3
ppe
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
H Uncu
Phlebology, 24(2), 56-60 (2009-03-21)
The optimal treatment of superficial vein thrombosis (SVT) of the leg has not been determined yet. The aim of this study is to evaluate the efficacy of low-molecular-weight heparin (LMWH) as compared with combined therapy of LMWH with an anti-inflammatory
G Gallacchi et al.
Praxis, 98(12), 635-642 (2009-06-11)
137 patients with active osteoarthritis of the knee joint were randomized in the ratio 2:1 to be treated with either one of the non-steroidal anti-inflammatory drugs acemetacin (180 mg/day) or indomethacin (150 mg/day). After 4 weeks of treatment, the complaints
Aracely E Chávez-Piña et al.
Annals of hepatology, 8(2), 141-147 (2009-06-09)
The pharmacokinetics of acemetacin, a non-steroidal anti-inflammatory drug which is biotransformed to indomethacin by hepatic first-pass effect, was examined during the necrotic and regeneration phases resulting from acute hepatitis induced by carbon tetrachloride (CCl4). Acute hepatitis was induced by oral
