B0760
丁苯羟酸
analytical standard
别名:
对丁氧苯乙酰氧肟酸
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关于此项目
经验公式（希尔记法）:
C12H17NO3
化学文摘社编号:
分子量:
223.27
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
EC Number:
219-451-1
MDL number:
InChI
1S/C12H17NO3/c1-2-3-8-16-11-6-4-10(5-7-11)9-12(14)13-15/h4-7,15H,2-3,8-9H2,1H3,(H,13,14)
InChI key
MXJWRABVEGLYDG-UHFFFAOYSA-N
SMILES string
CCCCOc1ccc(CC(=O)NO)cc1
grade
analytical standard
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
application(s)
forensics and toxicology
pharmaceutical (small molecule)
veterinary
format
neat
Quality Level
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General description
Bufexamac is a drug with antipyretic, analgesic and anti-inflammatory properties.
Application
Bufexamac may be used as a reference standard in the determination of bufexamac in pharmaceutical formulations using high-performance liquid chromatography (HPLC).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Other Notes
Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
存储类别
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Contact dermatitis caused by bufexamac sparing the eruption of herpes zoster.
Hidetsugu Fukuda et al.
The Journal of dermatology, 39(4), 405-407 (2011-09-29)
S M Langan et al.
Clinical and experimental dermatology, 34(1), 20-25 (2008-10-03)
Many interventions have been described for inherited epidermolysis bullosa (EB), but it is unclear which are beneficial. A systematic review of randomized controlled trials (RCTs) was performed to inform practice and highlight research gaps. The Cochrane Central Register of Controlled
Acute generalized exanthematous pustulosis induced by bufexamac in an atopic girl.
H Belhadjali et al.
Contact dermatitis, 58(4), 247-248 (2008-03-21)
A Schnuch et al.
Deutsche medizinische Wochenschrift (1946), 130(50), 2881-2886 (2005-12-13)
Bufexamac is a non-steroidal, anti-inflammatory drug used in the topical treatment of atopic dermatitis, stasis dermatitis and perianal eczema. The substance is known to cause severe allergic contact dermatitis (ACD) as an adverse effect (AE), which may be indistinguishable from
Katrin Kügler et al.
Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG, 3(12), 979-986 (2006-01-13)
Anogenital dermatoses (AGD) are common and often very distressing. Clinically it is often unclear if allergic contact dermatitis or irritant dermatitis is involved. In order to optimize therapy and prophylaxis, it is essential to identify relevant allergens or irritants. Data
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