B168
(±)-布他拉莫 盐酸盐
analytical standard, for drug analysis
别名:
AY 23028
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关于此项目
经验公式（希尔记法）:
C25H31NO · HCl
化学文摘社编号:
分子量:
397.98
UNSPSC Code:
41116107
PubChem Substance ID:
MDL number:
InChI
1S/C25H31NO.ClH/c1-24(2,3)25(27)13-14-26-16-21-19-9-5-4-7-17(19)11-12-18-8-6-10-20(23(18)21)22(26)15-25;/h4-10,21-22,27H,11-16H2,1-3H3;1H/t21-,22-,25-;/m0./s1
SMILES string
Cl.CC(C)(C)[C@]1(O)CCN2C[C@H]3c4ccccc4CCc5cccc([C@@H]2C1)c35
InChI key
QZRUMKUMFJJARD-AAJWHBHYSA-N
grade
analytical standard
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
application(s)
forensics and toxicology
pharmaceutical (small molecule)
veterinary
format
neat
Application
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
D Szabó et al.
Anticancer research, 18(4C), 3039-3044 (1998-08-26)
The effect of three different stereoisomer pairs of CNS (central nervous system) active compounds was studied on the activity of human mdr1 p-glycoprotein. The methotrimeprazine, clopenthixol and butaclamol isomers had an antiproliferative effect (ID50) on the mdr1 expressing cells at
Raluca-Ioana Stefan-van Staden et al.
Combinatorial chemistry & high throughput screening, 13(8), 690-693 (2010-04-30)
Butaclamol is an antipsychotic drug used in the treatment of schizophrenia. The macrocyclic antibiotics, vancomycin and teicoplanin, are proposed as chiral selectors for the design of the enantioselective, potentiometric membrane electrodes (EPMEs) for the assay of (-)butaclamol. The slopes of
A Varga et al.
Anticancer research, 21(4A), 2709-2712 (2001-11-29)
The efflux pump of multidrug resistant mdr cells have different sensitivities to some stereoisomeric forms of CNS-active compounds. The ABC transporters of mdr cells were more sensitive to (-)butaclamol than to its stereoisomeric counterpart (8), which may function to alter
C Meyer et al.
European journal of pharmacology, 347(2-3), 293-299 (1998-07-08)
Membrane progesterone binding sites have been purified recently from pig liver. Since progesterone is considered as an endogenous sigma (sigma) receptor ligand, these sites were characterized pharmacologically by ligands selective for sigma receptor and dopamine receptor binding sites, and by
Hong Wang et al.
Journal of neurochemistry, 96(3), 694-705 (2006-01-05)
Expression of brain-derived neurotrophic factor (BDNF) is sensitive to changes in oxygen availability, suggesting that BDNF may be involved in adaptive responses to oxidative stress. However, it is unknown whether or not oxidative stress actually increases availability of BDNF by
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