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线性分子式:
C6H5COONa
化学文摘社编号:
分子量:
144.10
NACRES:
NA.25
PubChem Substance ID:
eCl@ss:
39024301
UNSPSC Code:
12352107
EC Number:
208-534-8
MDL number:
Beilstein/REAXYS Number:
3572467
产品名称
苯甲酸钠, BioXtra, ≥99.5%
InChI key
WXMKPNITSTVMEF-UHFFFAOYSA-M
InChI
1S/C7H6O2.Na/c8-7(9)6-4-2-1-3-5-6;/h1-5H,(H,8,9);/q;+1/p-1
SMILES string
[Na+].[O-]C(=O)c1ccccc1
product line
BioXtra
assay
≥99.5%
form
powder
impurities
≤0.0005% Phosphorus (P)
≤0.1% Insoluble matter
mp
>300 °C (lit.)
solubility
H2O: 1 M, clear, colorless
anion traces
chloride (Cl-): ≤0.05%
sulfate (SO42-): ≤0.05%
cation traces
Al: ≤0.0005%
Ca: ≤0.01%
Cu: ≤0.0005%
Fe: ≤0.0005%
K: ≤0.10%
Mg: ≤0.005%
NH4+: ≤0.05%
Pb: ≤0.001%
Zn: ≤0.0005%
Quality Level
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Application
苯甲酸钠已用于测试对苯环利定(PCP)诱导小鼠运动活动的影响。
Biochem/physiol Actions
苯甲酸钠也有药物应用,是糖浆和透明片剂的组分。高水平的苯甲酸钠可能会触发组胺释放,也会引起细胞损伤。推荐用于尿素循环障碍的治疗。然而,高水平的苯甲酸钠可能导致甘氨酸缺乏,并可能施加神经调节作用。
General description
苯甲酸钠是一种安全的食品防腐剂,具有抑菌功能。分子量约为114.11 Da。苯甲酸钠用于烘焙产品、果汁和奶酪。它在肝脏中与甘氨酸结合,以马尿酸形式从尿液中排出。
Disclaimer
The product is not intended for use as a biocide under global biocide regulations, including but not limited to US EPA′s Federal Insecticide Fungicide and Rodenticide Act, European Biocidal Products Regulation, Canada’s Pest Management Regulatory Agency, Turkey’s Biocidal Products Regulation, Korea’s Consumer Chemical Products and Biocide Safety Management Act (K-BPR) and others.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2
存储类别
13 - Non Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
An Overview on the Effects of Sodium Benzoate as a Preservative in Food Products
Shahmohammadi M, et al.
Biotechnology and Health Sciences, 3(3), 7-11 (2016)
Modulating NMDA receptor function with D-amino acid oxidase inhibitors: understanding functional activity in PCP-treated mouse model
Sershen H, et al.
Neurochemical Research, 41(1-2), 398-408 (2016)
Benzoate and sorbate salts: a systematic review of the potential hazards of these invaluable preservatives and the expanding spectrum of clinical uses for sodium benzoate
Piper JD and Piper PW
Comprehensive Reviews in Food Science and Food Safety, 16(5), 868-880 (2017)
Matteo Gabba et al.
Biophysical journal, 118(2), 422-434 (2019-12-18)
We present a fluorescence-based approach for determination of the permeability of small molecules across the membranes of lipid vesicles and living cells. With properly designed experiments, the method allows us to assess the membrane physical properties both in vitro and in vivo.
Saurabh Khasnavis et al.
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology, 7(2), 424-435 (2011-06-28)
DJ-1 (PARK7) is a neuroprotective protein that protects cells from oxidative stress. Accordingly, loss-of-function DJ-1 mutations have been linked with a familial form of early onset Parkinson disease. Mechanisms by which DJ-1 level could be enriched in the CNS are
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