BCR265
二苯并[a,e]荧蒽
BCR®, certified reference material
等级
certified reference material
Agency
BCR®
制造商/商品名称
JRC
技术
HPLC: suitable
gas chromatography (GC): suitable
包装形式
neat
储存温度
2-8°C
SMILES字符串
c1ccc-2c(c1)-c3cc4ccccc4c5cc6ccccc6c-2c35
InChI
1S/C24H14/c1-3-9-17-15(7-1)13-22-19-11-5-6-12-20(19)23-18-10-4-2-8-16(18)14-21(17)24(22)23/h1-14H
InChI key
JHOWUOKQHJHGMU-UHFFFAOYSA-N
分析说明
For more information please see:
BCR265
BCR265
法律信息
BCR is a registered trademark of European Commission
警示用语：
Warning
危险声明
预防措施声明
危险分类
Carc. 2
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
C Malaveille et al.
Carcinogenesis, 5(10), 1263-1266 (1984-10-01)
Dibenzo[a,e]fluoranthene, its 7-hydroxy, 3,4- and 12,13-dihydrodiol metabolic derivatives as well as three synthetic, structurally related hydrocarbons, were tested for mutagenicity towards Salmonella typhimurium TA100 strain in the presence of 3-methylcholanthrene-treated rat and mouse liver post-mitochondrial supernatants. Of these compounds, the
O Perin-Roussel et al.
Carcinogenesis, 4(1), 27-32 (1983-01-01)
When dibenzo[a,e]fluoranthene (DBF) is incubated in vitro with mouse liver microsomes in the presence of calf thymus DNA, several metabolites bind covalently to DNA. The metabolite-nucleoside adducts were separated by h.p.l.c. after enzymatic hydrolysis. The elution profile of this chromatogram
O Perin-Roussel et al.
Carcinogenesis, 5(3), 379-383 (1984-03-01)
The presence of DNA-protein crosslinks was shown by the alkaline elution technique in cultured mouse fibroblasts treated with dibenzo[a,e]fluoranthene (DBF), a non-alternating carcinogenic PAH. The crosslinks appeared to be between DNA and protein, since the effect disappeared with proteinase treatment.
S Saguem et al.
Carcinogenesis, 4(7), 837-842 (1983-01-01)
The structural identification of nineteen metabolites of dibenzo[a,e]fluoranthene (DBF) obtained by incubation in rat and mouse liver microsomes, allows one to establish a qualitative and semi-quantitative metabolic chart, involving up to three distinct oxidative attacks. The primary steps lead to
O Périn-Roussel et al.
Cancer letters, 61(3), 207-213 (1992-01-31)
The formation of DNA adducts was investigated in mouse fibroblasts from two different tissues--embryos and adult lung--after incubation with dibenzo[a,e]fluoranthene (DBF) or its major proximate metabolites. The nuclease P1 modification of the 32P-postlabeling method was adapted for detection of DBF-DNA
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