C1290
氯磺丙脲
analytical standard, ≥97%
别名:
对氯苯磺酰丙脲
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关于此项目
经验公式（希尔记法）:
C10H13ClN2O3S
化学文摘社编号:
分子量:
276.74
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
EC Number:
202-314-5
MDL number:
InChI key
RKWGIWYCVPQPMF-UHFFFAOYSA-N
InChI
1S/C10H13ClN2O3S/c1-2-7-12-10(14)13-17(15,16)9-5-3-8(11)4-6-9/h3-6H,2,7H2,1H3,(H2,12,13,14)
SMILES string
CCCNC(=O)NS(=O)(=O)c1ccc(Cl)cc1
grade
analytical standard
assay
≥97%
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
application(s)
forensics and toxicology
pharmaceutical (small molecule)
format
neat
Quality Level
Gene Information
human ... ABCC8(6833), ALB(213), EPHX2(2053), KCNJ1(3758), KCNJ11(3767)
mouse ... Ephx2(13850)
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General description
Chlorpropamide is a drug that belongs to the sulfonylurea family. It is an effective candidate in the treatment of diabetes insipidus.
Application
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Repr. 2
存储类别
11 - Combustible Solids
wgk
WGK 3
ppe
Eyeshields, Gloves, type P3 (EN 143) respirator cartridges
Worst Pills, Best Pills: A Consumer's Guide to Preventing Drug-Induced Deat (2009)
Advances in Clinical Chemistry, Volume 17 (1975)
Qing Zhu et al.
Molecular pharmaceutics, 7(4), 1291-1300 (2010-06-17)
As a result of an increase in the number of emerging therapies with dissolution limited bioavailability, formulation strategies such as solid dispersions that enhance the rate of solubilization are of interest. In this study, the microstructure of solid dispersions prepared
Yury V Seryotkin et al.
Acta crystallographica. Section B, Structural science, 69(Pt 1), 77-85 (2013-02-01)
The crystal structure of the high-pressure polymorph (α') of an antidiabetic drug, chlorpropamide [4-chloro-N-(propylaminocarbonyl)benzenesulfonamide, C(10)H(13)ClN(2)O(3)S], which is formed at ~2.8 GPa from the α-polymorph (P2(1)2(1)2(1)) on hydrostatic compression in saturated ethanol solution, has been determined. As a result of the
Jer-Yen Yang et al.
Cancer research, 70(11), 4709-4718 (2010-05-21)
Drug resistance is a central challenge of cancer therapy that ultimately leads to treatment failure. In this study, we characterized a mechanism of drug resistance that arises to AZD6244, an established mitogen-activated protein/extracellular signal-regulated kinase kinase (MEK) 1/2 inhibitor currently
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