C2290
氯福克酚
analytical standard
别名:
叔辛酚氯
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关于此项目
经验公式（希尔记法）:
C21H26Cl2O
化学文摘社编号:
分子量:
365.34
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
EC Number:
253-632-6
MDL number:
format
neat
InChI key
HQVZOORKDNCGCK-UHFFFAOYSA-N
InChI
1S/C21H26Cl2O/c1-20(2,3)13-21(4,5)16-7-9-19(24)15(11-16)10-14-6-8-17(22)12-18(14)23/h6-9,11-12,24H,10,13H2,1-5H3
SMILES string
CC(C)(C)CC(C)(C)c1ccc(O)c(Cc2ccc(Cl)cc2Cl)c1
grade
analytical standard
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
application(s)
forensics and toxicology
pharmaceutical (small molecule)
veterinary
storage temp.
2-8°C
Quality Level
General description
Clofoctol is a drug, which belongs to the group of phenolic compounds. It is used as an effective antibacterial agent against gram positive bacteria. Its mode of action may involve the inhibition of the generation of adenosine triphosphate(ATP)required for the cell wall synthesis.
Application
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
存储类别
13 - Non Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Antimicrobial activity of "clofoctol" on microorganisms of the human oral cavity.
A Buogo
Giornale italiano di chemioterapia, 30(2-3), 101-117 (1983-05-01)
M del Tacca et al.
Biological research in pregnancy and perinatology, 4(4), 166-168 (1983-01-01)
The pharmacokinetics of clofoctol [(tetramethyl-1,1,3,3,butyl)-4-(dichloro-2,4-benzyl)-2-hydroxy-1-benzene ] was investigated in six healthy newborns and compared with the kinetic parameters of the drug in six healthy adults. The concentration of the drug in plasma was measured by means of an original sensitive
[Trials of the in vitro antibacterial activity of clofoctol and pharmacokinetic features].
A Buogo
Giornale italiano di chemioterapia, 28(1-2), 65-71 (1981-01-01)
M G Bellotti et al.
Giornale di batteriologia, virologia ed immunologia, 77(7-12), 131-136 (1984-07-01)
In this study the bactericidal activity of Clofoctol has been evaluated by "in vitro" technique against gram-positive against gram-positive microorganisms clinically isolated. The results show that MIC of Clofoctol is very close to its bactericidal activity, which could therefore be
GIDEON Guide to Antimicrobial Agents: 2017 edition (2017)
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