Merck
CN

C5149

Sigma-Aldrich

钙离子载体A23187 混合钙镁盐

Approximate 1:1 molar ratio Ca:Mg. Actual content given on label.

登录查看公司和协议定价

别名:
Calcimycin, Calcium Ionophore mixed calcium magnesium salt
经验公式(希尔记法):
C29H37N3O6
分子量:
523.62
MDL编号:
PubChem化学物质编号:

质量水平

检测方案

99% (TLC)

形式

powder

溶解性

chloroform/methanol: 10 mg/mL, clear, faintly yellow

application(s)

diagnostic assay manufacturing
hematology
histology

储存温度

2-8°C

SMILES string

[Mg++].[Ca++].CNc1ccc2oc(CC3OC4(CCC3C)OC(C(C)CC4C)C(C)C(=O)c5ccc[nH]5)nc2c1C(O)=O

InChI

1S/C29H37N3O6.Ca.Mg/c1-15-10-11-29(17(3)13-16(2)27(38-29)18(4)26(33)20-7-6-12-31-20)37-22(15)14-23-32-25-21(36-23)9-8-19(30-5)24(25)28(34)35;;/h6-9,12,15-18,22,27,30-31H,10-11,13-14H2,1-5H3,(H,34,35);;/q;2*+2

InChI key

HKVXGTQLKZNXPV-UHFFFAOYSA-N

正在寻找类似产品? Visit 产品对比指南

应用

Calcium Ionophore A23187 mixed calcium magnesium salt has been used as a calcium ionophore to increase the intracellular levels of calcium.
Ionophore highly selective for Ca2+. Potentiates responses to NMDA but not to quisqualate. In cell culture, stimulates nitric oxide production by calmodulin-dependent constitutive nitric oxide synthase.

象形图

Exclamation mark

警示用语:

Warning

危险分类

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

监管及禁止进口产品

分析证书(COA)

输入产品批号来搜索 分析证书(COA) 。批号可以在产品标签上"批“ (Lot或Batch)字后找到。

已有该产品?

为方便起见,与您过往购买产品相关的文件已保存在文档库中。

访问文档库

难以找到您所需的产品或批次号码?

在网站页面上,产品编号会附带包装尺寸/数量一起显示(例如:T1503-25G)。请确保 在“产品编号”字段中仅输入产品编号 (示例: T1503).

示例

T1503
货号
-
25G
包装规格/数量

其它示例:

705578-5MG-PW

PL860-CGA/SHF-1EA

MMYOMAG-74K-13

1000309185

输入内容 1.000309185)

遇到问题?欢迎随时联系我们技术服务 寻求帮助

批号可以在产品标签上"批“ (Lot或Batch)字后面找到。

Aldrich 产品

  • 如果您查询到的批号为 TO09019TO 等,请输入去除前两位字母的批号:09019TO。

  • 如果您查询到的批号含有填充代码(例如05427ES-021),请输入去除填充代码-021的批号:05427ES。

  • 如果您查询到的批号含有填充代码(例如 STBB0728K9),请输入去除填充代码K9的批号:STBB0728。

未找到您寻找的产品?

部分情况下,可能未在线提供COA。如果搜索不到COA,可在线索取。

索取COA

Method of transfection affects the cAMP-mediated induction of the RIIbeta subunit of protein kinase A in Sertoli cells: inhibition of response by increase in intracellullar calcium.
Gronning LM, et al.
European Journal of Endocrinology, 141, 75-82 (1999)
Stability of the acrosome of the brush-tailed possum (Trichosurus vulpecula) and tammar wallaby (Macropus eugenii) in vitro and after exposure to conditions and agents known to cause capacitation or acrosome reaction of eutherian spermatozoa.
Mate KE and Rodger JC
Journal of Reproduction and Fertility, 91, 41-48 (1991)
Fatima El-Assaad et al.
PLoS pathogens, 10(3), e1003839-e1003839 (2014-03-22)
In patients with cerebral malaria (CM), higher levels of cell-specific microparticles (MP) correlate with the presence of neurological symptoms. MP are submicron plasma membrane-derived vesicles that express antigens of their cell of origin and phosphatidylserine (PS) on their surface, facilitating
Reiya Taniguchi et al.
Nature communications, 6, 8545-8545 (2015-10-16)
In vertebrates, the iron exporter ferroportin releases Fe(2+) from cells into plasma, thereby maintaining iron homeostasis. The transport activity of ferroportin is suppressed by the peptide hormone hepcidin, which exhibits upregulated expression in chronic inflammation, causing iron-restrictive anaemia. However, due
Arthur Liesz et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 35(2), 583-598 (2015-01-16)
Acute brain lesions induce profound alterations of the peripheral immune response comprising the opposing phenomena of early immune activation and subsequent immunosuppression. The mechanisms underlying this brain-immune signaling are largely unknown. We used animal models for experimental brain ischemia as

我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门