D172405
N,N-二甲基-4-亚硝基苯胺
97%, powder or chunks
别名:
4-亚硝基-N,N-二甲基苯胺
产品名称
N,N-二甲基-4-亚硝基苯胺, ≥97%
质量水平
方案
≥97%
表单
powder or chunks
mp
85-87 °C (lit.)
溶解性
ethanol: 5% (green to very dark green)
应用
diagnostic assay manufacturing
hematology
histology
储存温度
room temp
SMILES字符串
CN(C)c1ccc(cc1)N=O
InChI
1S/C8H10N2O/c1-10(2)8-5-3-7(9-11)4-6-8/h3-6H,1-2H3
InChI key
CMEWLCATCRTSGF-UHFFFAOYSA-N
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应用
N,N-二甲基-4-亚硝基苯胺与咪唑一起用于检测细胞中单线态氧的形成。
生化/生理作用
N,N-二甲基-4-亚硝基苯胺用于检测单线态氧。单线态氧与咪唑反应，并通过氧化作用漂白 N,N-二甲基-4-亚硝基苯胺。漂白N,N-二甲基-4-亚硝基苯胺会在 438 nm 处观察到吸收减少。
警示用语：
Danger
危险分类
Acute Tox. 3 Oral - Eye Irrit. 2 - Self-heat. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
靶器官
Respiratory system
储存分类代码
4.2 - Pyrophoric and self-heating hazardous materials
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
法规信息
监管及禁止进口产品
此项目有
W C Yang et al.
Journal of environmental quality, 34(1), 336-341 (2005-01-14)
N-nitrosodimethylamine (NDMA), a potential carcinogen, was commonly found in treated wastewater as a by-product of chlorination. As treated water is increasingly used for landscape irrigation, there is an imperative need to understand the leaching risk for NDMA in landscape soils.
Amanda M Woods et al.
Behavioral neuroscience, 120(5), 1159-1162 (2006-10-04)
The effect of D-cycloserine (DCS), an NMDA partial agonist, on extinction of fear was investigated in rats using the conditioned emotional response preparation. Fear extinction was facilitated when the first 4 trials occurred with a 30-mg/kg dose of DCS. However
I Marie Schreiber et al.
Environmental science & technology, 39(10), 3811-3818 (2005-06-15)
The formation of the potent carcinogen, N-nitrosodimethylamine (NDMA), during chlorine disinfection has caused significant concern among drinking water and wastewater recycling utilities practicing intentional or unintentional chloramination. Previous research modeled NDMA formation as arising from a reaction between monochloramine and
S Kapur et al.
Molecular psychiatry, 7(8), 837-844 (2002-09-17)
Ketamine and PCP are commonly used as selective NMDA receptor antagonists to model the putative hypoglutamate state of schizophrenia and to test new antipsychotics. Recent findings question the NMDA receptor selectivity of these agents. To examine this further, we measured
Juliette Gafni et al.
Toxicological sciences : an official journal of the Society of Toxicology, 77(1), 72-82 (2003-11-06)
The mechanisms by which non-coplanar 2,2',3,5',6-pentachlorobiphenyl (PCB 95) and rapamycin interact with ryanodine receptor (RyR) complexes to alter Ca2+ signaling, were explored in intact cerebellar granule neurons. PCB 95 (10 microM, 20 min) significantly increased the number of neurons responding
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