D7512
达克罗宁 盐酸盐
别名:
1-(4-丁氧基苯)-3-(1-呱啶基)-1-丙酮
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关于此项目
经验公式（希尔记法）:
C18H27NO2 · HCl
化学文摘社编号:
分子量:
325.87
UNSPSC Code:
41116107
PubChem Substance ID:
EC Number:
208-633-6
MDL number:
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
format
neat
SMILES string
Cl.CCCCOc1ccc(cc1)C(=O)CCN2CCCCC2
InChI
1S/C18H27NO2.ClH/c1-2-3-15-21-17-9-7-16(8-10-17)18(20)11-14-19-12-5-4-6-13-19;/h7-10H,2-6,11-15H2,1H3;1H
InChI key
KNZADIMHVBBPOA-UHFFFAOYSA-N
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Application
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Biochem/physiol Actions
经皮肤吸收，快速起效的局部麻醉剂
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 3 Oral - Eye Dam. 1 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
法规信息
新产品
此项目有
Nonprescription drug screening. Dyclonine hydrochloride.
L A Nelson
American pharmacy, NS27(9), 27-29 (1987-09-01)
Dyclonine hydrochloride, local anaesthetic allergic contact dermatitis.
H I Maibach
Contact dermatitis, 14(2), 114-114 (1986-02-01)
Andrea C Schmidt
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 25(4-5), 407-416 (2005-05-18)
Two homologous local anaesthetic drugs, falicaine (propipocaine) hydrochloride (1-(4-propoxyphenyl)-3-(1-piperidinyl)-1-propanone hydrochloride, PPCHC) and dyclonine hydrochloride (1-(4-butoxyphenyl)-3-(1-piperidinyl)-1-propanone hydrochloride, DCNHC) were characterized by thermal analysis (hot-stage-microscopy, differential scanning calorimetry, thermogravimetry), vibrational spectroscopic methods (FTIR-, FT-Raman-spectroscopy), powder X-ray diffractometry, solid-state-/solution-NMR and water-vapor sorption analysis.
N B Choudry et al.
The European respiratory journal, 3(5), 579-583 (1990-05-01)
Cough and airway constriction are common features of respiratory diseases. Both can be caused by stimulation of airway nerves. We have studied the effects of airway anaesthesia on these reflexes, stimulated by inhaled capsaicin, in order to determine whether they
S Weinstein et al.
The International journal of neuroscience, 54(1-2), 125-132 (1990-09-01)
The hypothesis that deficits in orotactile sensitivity may affect gustation and palatability is not new. It is supported by animal models employing deafferentation; however, little direct evidence supports the application of the model to humans. Indirect evidence comes from four
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