F6270
非哌西特 盐酸盐
analytical standard
别名:
1-(2-[4-氯苯氧基]乙酰基)-4-(3,4-亚甲基二氧苄基)哌嗪
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关于此项目
经验公式（希尔记法）:
C20H21ClN2O4 · HCl
化学文摘社编号:
分子量:
425.31
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
EC Number:
251-857-4
MDL number:
grade
analytical standard
Quality Level
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
application(s)
forensics and toxicology
pharmaceutical (small molecule)
veterinary
format
neat
SMILES string
Cl.Clc1ccc(OCC(=O)N2CCN(CC2)Cc3ccc4OCOc4c3)cc1
InChI
1S/C20H21ClN2O4.ClH/c21-16-2-4-17(5-3-16)25-13-20(24)23-9-7-22(8-10-23)12-15-1-6-18-19(11-15)27-14-26-18;/h1-6,11H,7-10,12-14H2;1H
InChI key
MVOWQBJZZKOQNU-UHFFFAOYSA-N
Application
有关适用仪器技术的更多信息，请参考产品分析证书。如需进一步支持，请联系技术服务部门。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
L Lucchi et al.
Brain research, 398(1), 212-214 (1986-11-19)
The release of Met-enkephalin immunoreactive material (ME-IR) from rat striatal slices is affected by exposure to amphetamine and fipexide (chloro-4-phenoxy)-2-acetyl-1-(methylene-dioxy 3, 4-benzyl-4-piperazine) a psychostimulant drug with mild dopaminomimetic activity. Both amphetamine and fipexide inhibited in vitro the release of ME-IR.
André Leblanc et al.
Rapid communications in mass spectrometry : RCM, 24(9), 1241-1250 (2010-04-15)
Drug bioactivation leading to the formation of reactive species capable of covalent binding to proteins represents an important cause of drug-induced toxicity. Reactive metabolite detection using in vitro microsomal incubations is a crucial step in assessing potential toxicity of pharmaceutical
Roland F Staack et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 804(2), 337-343 (2004-04-15)
Qualitative studies are described on the metabolism and the toxicological analysis of the nootropic fipexide (FIP) in rat urine using gas chromatography-mass spectrometry (GC-MS). FIP was extensively metabolized to 1-(3,4-methylenedioxybenzyl)piperazine (MDBP), 4-chlorophenoxyacetic acid, 1-[2-(4-chlorophenoxy)acetyl]piperazine, N-(4-hydroxy-3-methoxy-benzyl)piperazine, piperazine, N-(3,4-methylenedioxybenzyl)ethylenediamine, and N-[2-(4-chlorophenoxy)acetyl]ethylenediamine. The