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Merck
CN

I3261

Indo 1-AM

93 - 100% purity

别名:

4-(6-Carboxy-2-indolyl)-4′-methyl-2,2′-(ethylenedioxy)dianiline-N,N,N′,N′-tetraacetic acid tetrakis(acetoxymethyl) ester

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关于此项目

经验公式(希尔记法):
C47H51N3O22
化学文摘社编号:
分子量:
1009.91
PubChem Substance ID:
UNSPSC Code:
12171500
MDL number:
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产品名称

Indo 1-AM, ~95% (HPLC)

InChI

1S/C47H51N3O22/c1-28-7-11-39(49(19-43(56)68-23-63-29(2)51)20-44(57)69-24-64-30(3)52)41(15-28)61-13-14-62-42-18-35(37-16-34-8-9-36(17-38(34)48-37)47(60)72-27-67-33(6)55)10-12-40(42)50(21-45(58)70-25-65-31(4)53)22-46(59)71-26-66-32(5)54/h7-12,15-18,48H,13-14,19-27H2,1-6H3

SMILES string

CC(=O)OCOC(=O)CN(CC(=O)OCOC(C)=O)c1ccc(C)cc1OCCOc2cc(ccc2N(CC(=O)OCOC(C)=O)CC(=O)OCOC(C)=O)-c3cc4ccc(cc4[nH]3)C(=O)OCOC(C)=O

InChI key

CAWBRCOBJNWRLK-UHFFFAOYSA-N

assay

~95% (HPLC)

fluorescence

λex 330 nm; λem 450 nm (with Calcium), λex 356 nm; λem 478 nm in methanol

storage temp.

−20°C

Quality Level

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Application

细胞可渗透性Ca2+荧光探针;亲和力低于FURA 2;使荧光发射在Ca2+结合后从482 nm大幅转变为398 nm。

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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CD2 sets quantitative thresholds in T cell activation.
Bachmann MF
The Journal of Experimental Medicine, 190, 1383-1383 (1999)
Methods in Cellular Imaging, Methods in Physiology (2013)
Simultaneous recording of calcium transients and reactive oxygen intermediates of human polymorphonuclear granulocytes in response to formyl-Met-Leu-Phe and the environmental agent sulfite.
Grundler W
Cytometry, 40, 219-219 (2000)
E Roux et al.
American journal of respiratory cell and molecular biology, 19(3), 437-444 (1998-09-09)
We have previously observed that acrolein administered ex vivo to isolated airways alters the subsequent airway responsiveness. To examine the cellular mechanisms involved in this alteration, we have studied the effect of acrolein exposure on calcium signaling in myocytes freshly
T Guenoun et al.
Anesthesiology, 92(2), 542-549 (2000-02-26)
Propofol is considered to be an anesthetic agent with few or no negative inotropic effects. This study evaluated a possible direct depressant effect of propofol on sarcoplasmic reticulum Ca2+ accumulation and cardiomyocytes. The effects of propofol on intracellular Ca2+ transients

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