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Merck
CN

M1845000

美曲磷酯

European Pharmacopoeia (EP) Reference Standard

别名:

三氯磷酸酯, (2,2,2-三氯-1-羟乙基)磷酸二甲酯, 美曲磷酯

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关于此项目

经验公式(希尔记法):
C4H8Cl3O4P
化学文摘社编号:
分子量:
257.44
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
1709434
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grade

pharmaceutical primary standard

API family

trichlorfon, metrifonate

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

COP(=O)(OC)C(O)C(Cl)(Cl)Cl

InChI

1S/C4H8Cl3O4P/c1-10-12(9,11-2)3(8)4(5,6)7/h3,8H,1-2H3

InChI key

NFACJZMKEDPNKN-UHFFFAOYSA-N

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Metrifonate EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.


signalword

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Resp. Sens. 1 - Skin Sens. 1

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

农药列管产品
危险化学品

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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H Feldmeier et al.
Arzneimittel-Forschung, 49(7), 557-565 (1999-08-12)
A systematic analysis of the existing literature has been undertaken to compare the therapeutic and operational profiles of metrifonate (CAS 52-68-6), and praziquantel (CAS 55-268-74-1), two anti-schistosomal compounds. The criteria evaluated were therapeutic efficacy against Schistosoma haematobium and other helminths
Metrifonate.
H M Lamb et al.
Drugs & aging, 11(6), 490-496 (1997-12-31)
M W Jann
Pharmacotherapy, 18(2 Pt 2), 55-67 (1998-04-16)
Alzheimer's disease is a chronic neurodegenerative disorder that is characterized by memory impairment, cognitive dysfunction, behavioral disturbances, and deficits in activities of daily living. A consistent observation in these patients is that cholinergic neurons are affected and deteriorate over time



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货号GTIN
M184500004061833812822