M3157
米那卜林 二盐酸盐
analytical standard
别名:
N-(4-甲基-6-苯基-3-哒嗪基)-4-吗啉乙胺
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关于此项目
经验公式（希尔记法）:
C17H22N4O · 2HCl
化学文摘社编号:
分子量:
371.30
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
EC Number:
247-329-8
MDL number:
grade
analytical standard
Quality Level
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
application(s)
forensics and toxicology
pharmaceutical (small molecule)
format
neat
SMILES string
Cl.Cl.Cc1cc(nnc1NCCN2CCOCC2)-c3ccccc3
InChI
1S/C17H22N4O.2ClH/c1-14-13-16(15-5-3-2-4-6-15)19-20-17(14)18-7-8-21-9-11-22-12-10-21;;/h2-6,13H,7-12H2,1H3,(H,18,20);2*1H
InChI key
GNUCGROXDZMCJI-UHFFFAOYSA-N
Gene Information
human ... ACHE(43), CHRM1(1128), DRD2(1813), HTR2B(3357), HTR2C(3358), MAOA(4128), SLC6A4(6532)
rat ... Ache(83817), Camk2a(25400), Prkca(24680)
Application
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Biochem/physiol Actions
抗抑郁剂
C A Lorenzini et al.
Pharmacology, biochemistry, and behavior, 45(2), 481-485 (1993-06-01)
The nootropic activity of 3-(2-morpholino-ethylamino)-4-methyl-6-phenyl-pyridazine dihydrochloride (minaprine) has been investigated in intact male, adult Long Evans rats by means of an active avoidance paradigm. In the light-dark box apparatus, the rat had to learn the active avoidance response of going
A Imperato et al.
Neuroscience letters, 166(1), 69-72 (1994-01-17)
Subchronic (5 mg/kg daily for 9 consecutive days) but not acute minaprine treatment enhanced in vivo dopamine release in the limbic part of the striatum of rats as revealed by intracerebral microdialysis. Moreover, the same subchronic treatment with minaprine reduced
J G Edwards et al.
British journal of clinical pharmacology, 42(4), 491-498 (1996-10-01)
1. A double-blind, multicentre study comparing the efficacy and safety of minaprine and amitriptyline in patients with major depression was carried out. Five hundred and thirty-one patients were randomly assigned to treatment with either minaprine 100 mg, 200 mg or
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| M3157-1G | 04061826762226 |