M3761
甲硝唑
analytical standard
别名:
2-甲基-5-硝基咪唑-1-乙醇
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关于此项目
经验公式（希尔记法）:
C6H9N3O3
化学文摘社编号:
分子量:
171.15
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
207-136-1
Beilstein/REAXYS Number:
611683
MDL number:
产品名称
甲硝唑, analytical standard
InChI key
VAOCPAMSLUNLGC-UHFFFAOYSA-N
InChI
1S/C6H9N3O3/c1-5-7-4-6(9(11)12)8(5)2-3-10/h4,10H,2-3H2,1H3
SMILES string
CC1=NC=C([N+]([O-])=O)N1CCO
grade
analytical standard
form
crystalline
technique(s)
HPLC: suitable
gas chromatography (GC): suitable
mp
159-161 °C (lit.)
antibiotic activity spectrum
Gram-negative bacteria
parasites
application(s)
forensics and toxicology
pharmaceutical (small molecule)
format
neat
mode of action
DNA synthesis | interferes
storage temp.
2-8°C
Quality Level
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Application
此分析标准品可用于以下用途：
- 碳糊电极 (CPE) 循环伏安法测定三种不同品牌甲硝唑片中甲硝唑的含量
- 采用反相高效液相色谱-光电二极管阵列检测器（RP- HPLC-DAD)同时测定制药剂量的甲硝唑、二氯尼特、螺旋霉素和克利喹诺
- 开发基于聚多巴胺/羧基多壁碳纳米管(MWCNTs-COOH)纳米复合材料的电化学传感器，测定甲硝唑
- 液相色谱–离子阱质谱法(LC-MS/MS法分析在水、沉积物和鱼组织样本中的甲硝唑）
- 基于多壁碳纳米管 (MWCNT) 和壳聚糖-镍络合物 (CTS-Ni) 的电化学传感器测定片剂、人尿液和血清样品中的甲硝唑
General description
甲硝唑（Metronidazole）是一种硝基咪唑类药物，尤其适合用于治疗由厌氧菌和原生动物引起的人类和家畜感染。
Other Notes
有关合适的仪器技术的更多信息，请参阅产品′的检验报告。想要获得更多支持，请联系技术服务部。
signalword
Danger
hcodes
Hazard Classifications
Carc. 1B - Muta. 1B - STOT RE 2
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Alison L Huckenpahler et al.
Translational vision science & technology, 9(10), 18-18 (2020-09-29)
To observe and characterize cone degeneration and regeneration in a selective metronidazole-mediated ablation model of ultraviolet-sensitive (UV) cones in zebrafish using in vivo optical coherence tomography (OCT) imaging. Twenty-six sws1:nfsB-mCherry;sws2:eGFP zebrafish were imaged with OCT, treated with metronidazole to selectively
Sonja Löfmark et al.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 50 Suppl 1, S16-S23 (2010-01-14)
Metronidazole has been used for the treatment of infections for >45 years and is still successfully used for the treatment of trichomoniasis, amoebiasis, and giardiasis. Anaerobic bacterial infections caused by Bacteroides species, fusobacteria, and clostridia respond favorably to metronidazole therapy.
Manoj K Puthia et al.
Eukaryotic cell, 7(3), 435-443 (2007-12-25)
Blastocystis is a ubiquitous enteric protozoan found in the intestinal tracts of humans and a wide range of animals. Evidence accumulated over the last decade suggests association of Blastocystis with gastrointestinal disorders involving diarrhea, abdominal pain, constipation, nausea, and fatigue.
Claire Chevalier et al.
Cell metabolism, 32(4), 575-590 (2020-09-12)
Osteoporosis is the most prevalent metabolic bone disease, characterized by low bone mass and microarchitectural deterioration. Here, we show that warmth exposure (34°C) protects against ovariectomy-induced bone loss by increasing trabecular bone volume, connectivity density, and thickness, leading to improved
T H I Brummer et al.
BJOG : an international journal of obstetrics and gynaecology, 120(10), 1269-1276 (2013-06-22)
To evaluate cefuroxime and metronidazole antibiotic prophylaxis. Observational nonrandomised 1-year prospective cohort study. Fifty-three hospitals in Finland. A total of 5279 women undergoing hysterectomy for benign indications, with cefuroxime given to 4301 and metronidazole given to 2855. Excluding other antibiotics
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