N2144
7-氯-5-(2-氟苯基)-1,3-二氢-3H-1,4-苯并二氮杂卓-2-酮
analytical standard
别名:
脱烃基氟胺安定
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关于此项目
经验公式（希尔记法）:
C15H10ClFN2O
化学文摘社编号:
分子量:
288.70
UNSPSC Code:
41116107
PubChem Substance ID:
EC Number:
220-748-3
MDL number:
InChI key
UVCOILFBWYKHHB-UHFFFAOYSA-N
InChI
1S/C15H10ClFN2O/c16-9-5-6-13-11(7-9)15(18-8-14(20)19-13)10-3-1-2-4-12(10)17/h1-7H,8H2,(H,19,20)
SMILES string
Fc1ccccc1C2=NCC(=O)Nc3ccc(Cl)cc23
grade
analytical standard
assay
≥98%
drug control
USDEA Schedule IV; Home Office Schedule 4.1; psychotrope (France); regulated under CDSA - not available from Sigma-Aldrich Canada
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
application(s)
forensics and toxicology
pharmaceutical (small molecule)
format
neat
Application
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Biochem/physiol Actions
氟胺安定的主要人体代谢物
signalword
Warning
hcodes
Hazard Classifications
STOT SE 3
target_organs
Central nervous system
存储类别
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Katharina Koch et al.
Drug testing and analysis (2018-04-11)
Novel synthetic opioids and benzodiazepines are an emerging trend on the narcotic drugs market. We present a lethal case of U-47700 and flubromazepam poisoning. A 24-year-old man suffered apnoea after the consumption of the synthetic opioid U-47700 in combination with
S Dunlop et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 1064, 22-27 (2017-09-11)
The objective of this work was to establish an analytical method for the analysis of 7 Benzodiazepines (diazepam, oxazepam, temazepam, nordiazepam, desalkylflurazepam, alprazolam and α-hydroxyalprazolam) in urine specimens taken from drivers suspected of driving under the influence of drugs. The
Hyojeong Kim et al.
Forensic science international, 282, 13-23 (2017-11-15)
The aim of this study was to investigate the correlation between histories of zolpidem and benzodiazepines use and their concentrations in hair as determined by segmental hair analysis, that is, by analyzing hair samples taken 0-1, 1-2, 2-3, 3-4, 4-5
W Sieghart
Neuroscience letters, 38(1), 73-78 (1983-07-15)
The potency of several new benzodiazepines as inhibitors of [3H]flunitrazepam binding was investigated in membranes from rat cerebellum or hippocampus. It was found that quazepam and two of its metabolites have a higher affinity for benzodiazepine receptors in cerebellum than
Kimiyasu Kato et al.
Therapeutic drug monitoring, 25(4), 473-477 (2003-07-29)
The effects of itraconazole, a potent inhibitor of cytochrome P450 (CYP) 3A4, on the plasma kinetics of quazepam and its two active metabolites after a single oral dose of the drug were studied. Ten healthy male volunteers received itraconazole 100
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