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Merck
CN

P2307

聚乙烯吡咯烷酮

suitable for plant cell culture, average mol wt 10,000

别名:

PVP, 聚维酮

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关于此项目

线性分子式:
(C6H9NO)n
化学文摘社编号:
NACRES:
NA.71
PubChem Substance ID:
UNSPSC Code:
12352207
MDL number:
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产品名称

聚乙烯吡咯烷酮, suitable for plant cell culture, average mol wt 10,000

Quality Level

InChI

1S/C6H9NO/c1-2-7-5-3-4-6(7)8/h2H,1,3-5H2

SMILES string

C=CN1CCCC1=O

InChI key

WHNWPMSKXPGLAX-UHFFFAOYSA-N

form

powder

mol wt

average mol wt 10,000

technique(s)

cell culture | plant: suitable

viscosity number

12-18(lit.)

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Application


  • Design and development of a soluble PDA-Emodin-PVP-MN patch and its anti-obesity effect in rats.:本文开发了一种含聚乙烯吡咯烷酮(PVP)的微针贴片,增强抗肥胖药物递送,说明PVP可加入药物制剂提高药物的溶解度和疗效(Wang H et al., 2024)。

  • Polyvinylpyrrolidone Assisted One-Pot Synthesis of Size-Tunable Cocktail Nanodrug for Multifunctional Combat of Cancer.:PVP可作为稳定剂和调节剂,在复方纳米药物(nanodrug cocktail)合成中发挥关键作用。这种药物可有效地靶向治疗癌症,优化疗效(Wang C et al., 2024)。

  • Biochemical parameters, oxidative stress biomarkers, and anatomopathological changes in Wistar rats treated with 3′-demethoxy-6-O-demethylisoguaiacin and norisoguaiacin.:在生物医学应用中,PVP可用于提高特定生物活性药物的溶解度和生物利用度(Flores Jimenez NG et al., 2024)。

  • A water-soluble preparation for intravenous administration of isorhamnetin and its pharmacokinetics in rats.:PVP可用于制备水溶性药物制剂以促进疏水性物质的静脉递送,说明它具有改善药物递送系统的应用前景(Rassu G et al., 2024)。

  • Activation of the PPAR gamma/NF-kB pathway by A-MPDA@Fe(3)O(4)@PVP via scavenging reactive oxygen species to alleviate hepatic ischemia-reperfusion injury.:一项创新研究,开发有效减少氧化应激的纳米粒系统。其中PVP用于稳定该系统,说明它的治疗应用潜能(Mo D et al., 2024)。

Other Notes

聚乙烯吡咯烷酮是 Denhardt′s 溶液的一种成分,在标准 50X 储备溶液中的浓度为 1%(w/v)。

存储类别

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Katja A Lüders et al.
Glia, 67(4), 634-649 (2019-01-15)
Proteolipid protein (PLP) is the most abundant integral membrane protein in central nervous system (CNS) myelin. Expression of the Plp-gene in oligodendrocytes is not essential for the biosynthesis of myelin membranes but required to prevent axonal pathology. This raises the
Abeer Maher Fayyad et al.
International journal of molecular sciences, 20(7) (2019-04-04)
Obesity is a major risk for diabetes. Brown adipose tissue (BAT) mediates production of heat while white adipose tissue (WAT) function in the storage of fat. Roles of BAT in the treatment of obesity and related disorders warrants more investigation.
Aaron R Jex et al.
Journal of clinical microbiology, 46(7), 2252-2262 (2008-05-02)
In the present study, we analyzed genetic variation in Cryptosporidium species from humans (n = 62) with clinical cryptosporidiosis in South Australia. Sequence variation was assessed in regions within the small subunit of nuclear rRNA (p-SSU), the 70-kDa heat shock
Nicole M Sanders et al.
American journal of physiology. Endocrinology and metabolism, 294(5), E853-E860 (2008-03-13)
Selective serotonin reuptake inhibitors (SSRIs) are widely prescribed for patients with comorbid diabetes and depression. Clinical case studies in diabetic patients, however, suggest that SSRI therapy may exacerbate hypoglycemia. We hypothesized that SSRIs might increase the risk of hypoglycemia by
Helen Thomas et al.
Journal of chromatography. A, 1285, 48-56 (2013-03-16)
In protein chromatography, the size of the protein determines which fraction of pores it can access within a resin and at which rate of diffusion. Moreover, in the presence of grafted polymers like in advanced materials, adsorbed proteins and electrolytes

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