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Merck
CN

PHR1299

Supelco

Pamabrom

Pharmaceutical Secondary Standard; Certified Reference Material

别名:

Pamabrom, PAM

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化学文摘社编号:
EC 号:
UNSPSC代码:
41116107
NACRES:
NA.24
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等级

certified reference material
pharmaceutical secondary standard

质量水平

Agency

traceable to USP 1077708

API类

pamabrom

CofA

current certificate can be downloaded

技术

HPLC: suitable
gas chromatography (GC): suitable

应用

pharmaceutical (small molecule)

包装形式

neat

储存温度

2-30°C

InChI

1S/C7H7BrN4O2.C4H11NO/c1-11-4-3(9-6(8)10-4)5(13)12(2)7(11)14;1-4(2,5)3-6/h1-2H3,(H,9,10);6H,3,5H2,1-2H3

InChI key

ATOTUUBRFJHZQG-UHFFFAOYSA-N

一般描述

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Pamabrom is a weak diuretic which is used as an analgesic and an antihistamine for symptomatic control of the premenstrual syndrome. It typically assists in the reduction of bloating associated with premenstrual syndrome.

应用

Pamabrom may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by chromatography techniques.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

分析说明

These secondary standards offer multi-traceability to the US and EP primary standards, where they are available.

其他说明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAA0585 in the slot below. This is an example certificate only and may not be the lot that you receive.

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Acute Tox. 4 Oral

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

监管及禁止进口产品
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Rp-Lc and TLc Densitometric Determination of paracetamol and pamabrom in presence of Hazardous Impurity of paracetamol and Application to pharmaceuticals
El-Houssini OM
Analytical Chemistry Insights, 8, ACI-S12349 (2013)
Mario I Ortiz
European journal of obstetrics, gynecology, and reproductive biology, 152(1), 73-77 (2010-05-19)
To evaluate the prevalence, impact and treatment of primary dysmenorrhea among Mexican university students. A multiple-choice questionnaire was administered to 1539 students in six university programs: medicine, nursing, nutrition, dentistry, pharmacy and psychology. Data on the presence, severity, symptoms, treatment
Fixed drug eruptions and oral rechallenge.
K Kauppinen
Cleveland Clinic journal of medicine, 58(1), 64-65 (1991-01-01)
Guillermo Di Girolamo et al.
Expert opinion on pharmacotherapy, 5(3), 561-570 (2004-03-12)
Primary dysmenorrhoea is the most frequent gynaecological condition, with a prevalence of 40 - 90% in women within the reproductive age. It is characterised by cyclic pelvic pain related to menstrual period, vomiting and headache. As prostaglandins and leukotrienes appear
Fixed drug eruption caused by pamabrom.
J A Min et al.
Clinical and experimental dermatology, 34(7), e455-e456 (2009-08-18)

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