InChI key
SOXAGEOHPCXXIO-UHFFFAOYSA-N
InChI
1S/C17H25NO2/c1-11(2)13-9-8-12(3)10-16(13)20-17(19)14-6-4-5-7-15(14)18/h4-7,11-13,16H,8-10,18H2,1-3H3
SMILES string
CC(C)C1CCC(C)CC1OC(=O)c2ccccc2N
grade
certified reference material, pharmaceutical secondary standard
agency
traceable to USP 1381742
API family
meradimate
CofA
current certificate can be downloaded
packaging
ampule of 1 × 1 g
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
refractive index
n20/D 1.542 (lit.)
bp
177-179 °C/3 mmHg (lit.)
density
1.04 g/mL at 25 °C (lit.)
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
2-8°C
Quality Level
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General description
Menthyl anthranilate, popularly known as meradimate, is a broad-spectrum UV sunscreen agent. It is commonly used in personal care products including sunscreens, hair care, and cosmetic products.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Application
Menthyl anthranilate may be used as a pharmaceutical reference standard for the determination of the analyte in raw materials and personal care products by high performance liquid chromatography and gas chromatography.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Other Notes
To see an example of a Certificate of Analysis for this material enter LRAA3647 in the slot below. This is an example certificate only and may not be the lot that you receive.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
10 - Combustible liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Wavepacket insights into the photoprotection mechanism of the UV filter methyl anthranilate
Rodrigues NDN, et al.
Nature Communications, 9(1), 5188-5188 (2018)
Determination of sunscreen compounds in topical sunscreen products
DiNunzio JE and Gadde RR
Journal of Chromatography A, 519(1), 117-124 (1990)
Simultaneous analysis and monitoring of 16 UV filters in cosmetics by high-performance liquid chromatography.
Kim D, et al.
Journal of Cosmetic Science, 63(2), 103-117 (2012)
Optimization of an analytical methodology for the simultaneous determination of different classes of ultraviolet filters in cosmetics by pressurized liquid extraction-gas chromatography tandem mass spectrometry
Vila M, et al.
Journal of Chromatography A, 1405(1), 12-22 (2015)
Photophysics of the sunscreen ingredient menthyl anthranilate and its precursor methyl anthranilate: A bottom-up approach to photoprotection
Rodrigues NDN, et al.
Journal of Photochemistry and Photobiology A: Chemistry, 353(1), 376-384 (2018)
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