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Merck
CN

PHR1704

萘夫西林钠盐

Pharmaceutical Secondary Standard; Certified Reference Material

别名:

萘夫西林钠盐 钠盐 一水合物

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关于此项目

线性分子式:
C21H21N2O5SNa · H2O
化学文摘社编号:
7177-50-6
分子量:
454.47
NACRES:
NA.24
PubChem Substance ID:
329823567
UNSPSC Code:
41116107
MDL number:
MFCD01941128

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CofA

current certificate can be downloaded

InChI

1S/C21H22N2O5S.Na.H2O/c1-4-28-13-10-9-11-7-5-6-8-12(11)14(13)17(24)22-15-18(25)23-16(20(26)27)21(2,3)29-19(15)23;;/h5-10,15-16,19H,4H2,1-3H3,(H,22,24)(H,26,27);;1H2/q;+1;/p-1/t15-,16+,19-;;/m1../s1

SMILES string

O.[Na+].CCOc1ccc2ccccc2c1C(=O)N[C@H]3C4SC(C)(C)[C@@H](N4C3=O)C([O-])=O

InChI key

OCXSDHJRMYFTMA-KMFBOIRUSA-M

grade

certified reference material, pharmaceutical secondary standard

agency

traceable to USP 1450007

API family

nafcillin

packaging

pkg of 1 g

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

-10 to -25°C

Quality Level

300

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General description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Nafcillin Sodium is a narrow-spectrum β-lactamase resistant antibiotic drug.

Application

Nafcillin Sodium may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by chromatography.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

pictograms

Health hazardExclamation mark
GHS08,GHS07

signalword

Danger

Hazard Classifications

Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

target_organs

Respiratory system

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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Nafcillin Sodium
USP42-NF37
United States Pharmacopeia/National Formulary, 3029-3029 (2013)
Sensitive ion chromatographic determination of citrate and formate in pharmaceuticals
Kaleemullah T, et al.
Rasayan Journal of Chemistry, 4(4), 844-852 (2011)

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