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Merck
CN

Q4875

Sigma-Aldrich

Quin 2-AM

≥90%

别名:

2-[(2-Amino-5-methylphenoxy)methyl]-6-methoxy-8-aminoquinoline-N,N,N′,N′-tetraacetic acid tetrakis(acetoxymethyl ester), 2-{[2-Bis(carboxymethyl)amino-5-methylphenoxy]-methyl}-6-methoxy-8-bis(carboxymethyl)aminoquinoline tetrakis(acetoxymethyl) ester

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关于此项目

经验公式（希尔记法）:
C38H43N3O18
CAS Number:
83104-85-2
分子量:
829.76
Beilstein:
8181991
MDL编号:
MFCD00010285
UNSPSC代码:
12171500
PubChem化学物质编号:
24899332

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方案

≥90%

运输

dry ice

储存温度

−20°C

SMILES字符串

COc1cc(N(CC(=O)OCOC(C)=O)CC(=O)OCOC(C)=O)c2nc(COc3cc(C)ccc3N(CC(=O)OCOC(C)=O)CC(=O)OCOC(C)=O)ccc2c1

InChI

1S/C38H43N3O18/c1-23-7-10-31(40(14-34(46)56-19-52-24(2)42)15-35(47)57-20-53-25(3)43)33(11-23)51-18-29-9-8-28-12-30(50-6)13-32(38(28)39-29)41(16-36(48)58-21-54-26(4)44)17-37(49)59-22-55-27(5)45/h7-13H,14-22H2,1-6H3

InChI key

ANRZUBSJAOAXHS-UHFFFAOYSA-N

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应用

Cell permeable fluorescent probe for Ca2+ that gives a large shift in the UV absorption spectrum and a 20-fold increase in fluorescence upon Ca2+ binding

储存分类代码

10 - Combustible liquids

WGK

WGK 3

闪点(°F)

235.4 °F - closed cup

闪点(°C)

113 °C - closed cup

个人防护装备

Eyeshields, Gloves, type ABEK (EN14387) respirator filter

法规信息

新产品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
SLBB7894V
071M1365V
031M1438V
011M1337V
019K1800

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Marine de Marcken et al.
Science signaling, 12(605) (2019-10-31)
Human blood CD14+ monocytes are bone marrow-derived white blood cells that sense and respond to pathogens. Although innate immune activation by RNA viruses preferentially occurs through intracellular RIG-I-like receptors, other nucleic acid recognition receptors, such as Toll-like receptors (TLRs), play
R Winokur et al.
Blood, 85(7), 1796-1804 (1995-04-01)
The so-called cold activation of platelets that precludes refrigeration of platelets for storage has long been recognized, but its mechanism has remained a mystery. Cooling of discoid resting platelets to temperatures below 15 degrees C causes shape distortions, and the
Y Yatomi et al.
Biochemical and biophysical research communications, 171(1), 109-115 (1990-08-31)
Cytoplasmic Ca2+ mobilization in human platelets triggered by a CD 9 monoclonal antibody, TP82, was monitored by the Ca2(+)-sensitive photoprotein, aequorin and Ca2(+)-sensitive fluorophores, fura 2 and quin 2. Aequorin-indicated Ca2+ values were proportional to the concentration of TP82, which
J J Egan et al.
Journal of cellular biochemistry, 45(1), 101-111 (1991-01-01)
Parathyroid hormone (PTH) alters the shape of osteoblastic cells both in vivo and in vitro. In this study, we examined the effect of PTH on cytoskeletal actin and myosin, estimated by polyacrylamide gel electrophoresis of Triton X-100 (1%) nonextractable proteins.
L Carpenter-Deyo et al.
The Journal of pharmacology and experimental therapeutics, 258(2), 739-746 (1991-08-01)
To determine whether incubation for several hours with intracellular Ca++ indicators caused toxicity to freshly isolated hepatocytes from rats, cells were incubated under 95% O2-5% CO2 in medium containing 2 mM Ca++ and the acetoxymethyl (AM) esters of Quin 2
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