SMB01368
Octahydrocurcumin
≥95% (HPLC)
别名:
Hexahydrobisdemethoxycurcumin, Hexahydrocurcuminol, OHC
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关于此项目
经验公式（希尔记法）:
C21H28O6
化学文摘社编号:
分子量:
376.44
UNSPSC Code:
12352205
NACRES:
NA.21
MDL number:
SMILES string
O[C@H](C[C@@H](O)CCc2cc(c(cc2)O)OC)CCc1cc(c(cc1)O)OC
InChI
1S/C21H28O6/c1-26-20-11-14(5-9-18(20)24)3-7-16(22)13-17(23)8-4-15-6-10-19(25)21(12-15)27-2/h5-6,9-12,16-17,22-25H,3-4,7-8,13H2,1-2H3/t16-,17-/m0/s1
InChI key
OELMAFBLFOKZJD-IRXDYDNUSA-N
biological source
synthetic
assay
≥95% (HPLC)
form
solid
storage temp.
2-8°C
Quality Level
General description
Octahydrocurcumin (OHC) is an active metabolite of curcumin. OHC has shown anti-inflammatory activity and antioxidant effects on LPS-stimulated inflammation through inhibition of the NF-κB signaling pathway.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Zhen-Biao Zhang et al.
Frontiers in pharmacology, 9, 1181-1181 (2018-11-06)
Curcumin (CUR), a promising naturally occurring dietary compound, is commonly recognized as the potential anti-inflammatory agent. While the application of CUR was hampered by its low stability and poor systemic bioavailability, it has been suggested that the biological activities of
Qing-Feng Xie et al.
Evidence-based complementary and alternative medicine : eCAM, 2020, 8856135-8856135 (2021-01-12)
Curcumin (CUR) possesses pronounced anti-inflammatory and antioxidant activities. Generally, the clinical application of CUR is restricted due to its apparent unstability and poor absorption, and the biological activities of CUR may be closely associated with its metabolites. Tetrahydrocurcumin (THC) and
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