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Merck
CN

SMB01416

Fructoselysine hydrochloride

new

≥95%

别名:

ε-Fructoselysine, ε-N-Deoxyfructosyllysine, Nε-(1-Deoxy-D-fructos-1-yl)-L-lysine, Fructosyllysine

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关于此项目

经验公式(希尔记法):
C12H24N2O7 · xHCl
化学文摘社编号:
分子量:
308.33 (free base basis)
MDL编号:
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生物来源

synthetic

质量水平

方案

≥95%

表单

powder

颜色

faint yellow to yellow, to beige

沸点

654.5 °C ((Predicted) (Pressure: 760.00 Torr))

溶解性

DMF: soluble
DMSO: soluble
methanol: soluble

应用

general analytical
life science and biopharma
metabolomics

储存温度

−20°C

SMILES字符串

C([C@H]([C@@H]([C@@H](CO)O)O)O)(CNCCCC[C@@H](C(O)=O)N)=O

InChI

InChI=1S/C12H24N2O7/c13-7(12(20)21)3-1-2-4-14-5-8(16)10(18)11(19)9(17)6-15/h7,9-11,14-15,17-19H,1-6,13H2,(H,20,21)/t7-,9+,10+,11+/m0/s1

InChI key

BFSYFTQDGRDJNV-AYHFEMFVSA-N

一般描述

Fructoselysine, also known as Fructosyl-lysine, is an important glyco-amino acid formed through the non-enzymatic glycation of lysine with glucose via the Maillard reaction. As an Amadori product, it is a foundational intermediate in the development of advanced glycation end products (AGEs), compounds associated with aging, diabetes, and other chronic conditions.
This compound plays a crucial role in research on protein glycation, food chemistry, and metabolic disorders. Fructoselysine is also a precursor to glucosepane, a lysine-arginine protein cross-link used as a biomarker in diabetes detection. Its diverse biological and chemical properties make it invaluable for understanding glycation processes and their impact on human health.

应用

Fructoselysine could find application in: Protein Glycation Studies: Serves as a model system for investigating glycation reactions involving lysine, amino acids, and fatty acids.

Diabetes Research: A precursor to glucosepane, providing insights into diabetes-related protein modifications and AGE formation.

Food Chemistry: A marker for the Maillard reaction during food heating, contributing to flavor and browning while signaling nutritional changes.

特点和优势

Versatile and adaptable for wide variety of research and metabolomics applications.

法规信息

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分析证书(COA)

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