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Merck
CN

Y0000177

1,2,3,4-丁四醇

European Pharmacopoeia (EP) Reference Standard

别名:

1,2,3,4-赤丁四醇, 内消旋-1,2,3,4-四羟基丁烷, I-赤藓糖醇

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线性分子式:
HOCH2[CH(OH)]2CH2OH
化学文摘社编号:
分子量:
122.12
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
1719753
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InChI

1S/C4H10O4/c5-1-3(7)4(8)2-6/h3-8H,1-2H2/t3-,4+

SMILES string

OC[C@@H](O)[C@@H](O)CO

InChI key

UNXHWFMMPAWVPI-ZXZARUISSA-N

grade

pharmaceutical primary standard

API family

erythritol

manufacturer/tradename

EDQM

bp

329-331 °C (lit.)

mp

118-120 °C (lit.)

application(s)

cleaning products
cosmetics
food and beverages
personal care
pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Erythritol EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Biochem/physiol Actions

Tas1r3 基因的等位变异影响对该糖醇的行为味道反应,表明它是T1R3 受体配体。

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

存储类别

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Hee-Jung Moon et al.
Applied microbiology and biotechnology, 86(4), 1017-1025 (2010-02-27)
Erythritol, a four-carbon polyol, is a biological sweetener with applications in food and pharmaceutical industries. It is also used as a functional sugar substitute in special foods for people with diabetes and obesity because of its unique nutritional properties. Erythritol
Erythritol: a review of biological and toxicological studies.
W O Bernt et al.
Regulatory toxicology and pharmacology : RTP, 24(2 Pt 2), S191-S197 (1996-10-01)
Nidhi Singh et al.
Current pharmaceutical design, 13(11), 1161-1177 (2007-04-14)
The 2-C-methyl-D-erythritol-4-phosphate (MEP) pathway for isoprenoid biosynthesis has come under increased scrutiny as a target for novel antimalarial, antibacterial and herbicidal agents. 1-Deoxy-D-xylulose 5-phosphate reductoisomerase (DXR) is a key enzyme of the pathway that catalyzes the rearrangement and nicotinamide adenine
I C Munro et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 36(12), 1139-1174 (1998-12-23)
A critical and comprehensive review of the safety information on erythritol was undertaken. Numerous toxicity and metabolic studies have been conducted on erythritol in rats, mice and dogs. The toxicity studies consist of long-term feeding studies conducted to determine carcinogenic
Deepak Ganjewala et al.
Current issues in molecular biology, 11 Suppl 1, i35-i45 (2009-02-06)
Isoprenoids, also known as terpenoids, are biosynthesized by the condensation of the two C5 unit isopentenyl diphosphate (IPP) and isomer dimethylallyl diphosphate (DMAPP). Generally, plants use two separate pathways plastidial Methyl-erythritol-4-phosphate (MEP) and cytosolic acetate-mevalonate (MVA) pathways for formation of

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