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Merck
CN

Y0000480

Dibrompropamidine diisetionate

European Pharmacopoeia (EP) Reference Standard

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经验公式(希尔记法):
C21H30Br2N4O10S2
化学文摘社编号:
分子量:
722.42
UNSPSC代码:
41116107
NACRES:
NA.24
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等级

pharmaceutical primary standard

API类

dibrompropamidine

制造商/商品名称

EDQM

应用

pharmaceutical (small molecule)

包装形式

neat

SMILES字符串

[S](=O)(=O)(O)CCO.Brc1c(ccc(c1)\C(=N\[H])\N)OCCCOc2c(cc(cc2)\C(=N\[H])\N)Br

InChI

1S/C17H18Br2N4O2.C2H6O4S/c18-12-8-10(16(20)21)2-4-14(12)24-6-1-7-25-15-5-3-11(17(22)23)9-13(15)19;3-1-2-7(4,5)6/h2-5,8-9H,1,6-7H2,(H3,20,21)(H3,22,23);3H,1-2H2,(H,4,5,6)

InChI key

BZACJASHKPPTKX-UHFFFAOYSA-N

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一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

应用

Dibrompropamidine diisetionate EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

包装

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

其他说明

Sales restrictions may apply.

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Allergic contact dermatitis from dibrompropamidine cream.
C Lützow-Holm et al.
Contact dermatitis, 18(2), 100-101 (1988-02-01)
K McClellan et al.
The British journal of ophthalmology, 71(10), 734-736 (1987-10-01)
A previously healthy 53-year-old man had keratitis of the right eye for six months, unresponsive to topical medical therapy. Acanthamoeba was grown from tissue obtained by corneal biopsy and from aqueous from an anterior chamber tap. The patient was treated
P Plesiat et al.
Journal of bacteriology, 179(22), 7004-7010 (1997-11-26)
Testosterone (a strongly hydrophobic steroid) and testosterone hemisuccinate (a negatively charged derivative) were used as probes to investigate alterations in the outer membrane of Pseudomonas aeruginosa. Diffusion rates of the steroids across the lipid bilayer were measured by coupling the
Acanthamoeba keratitis: 2007: a train wreck in slow motion.
H Dwight Cavanagh
Eye & contact lens, 33(5), 209-209 (2007-09-18)
P J McCluskey et al.
Eye (London, England), 7 ( Pt 1), 80-83 (1993-01-01)
Microsporidia are rare human opportunistic pathogens that are now increasingly recognised in patients with AIDS, most commonly as an ocular or enteric pathogen. This paper reports a case of microsporidial keratoconjunctivitis in a patient with AIDS which responded to treatment

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