等级
ACS reagent (primary standard)
质量水平
蒸汽压
0 hPa ( 66 °C)
方案
99.95-100.05%
表单
powder
反应适用性
reagent type: catalyst
core: arsenic
灼烧残渣
≤0.02%
溶解性
dilute HCl: insoluble ≤0.01%
痕量阴离子
S2-: passes test (lim. ~0.001%)
chloride (Cl-): ≤0.005%
痕量阳离子
Fe: ≤5 ppm
Pb: ≤0.002%
Sb: ≤0.05%
SMILES字符串
O=[As]O[As]=O
InChI
1S/As2O3/c3-1-5-2-4
InChI key
IKWTVSLWAPBBKU-UHFFFAOYSA-N
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一般描述
氧化砷(III),也称为三氧化二砷,是一种可用作合成多种砷基化合物原料的两性氧化物。
应用
氧化砷(III)可用于:
- 在封闭体系中通过静态氟化法合成五氟化砷(AsF5)。
- 在醋酸锌、2-甲氧基乙醇和单乙醇胺中加入As2O3,通过溶胶-凝胶自旋涂覆法制备砷掺杂 ZnO 薄膜。
警示用语:
Danger
危险分类
Acute Tox. 2 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 1A - Eye Dam. 1 - Skin Corr. 1B - STOT RE 1
靶器官
Respiratory system,Cardio-vascular system,Gastrointestinal tract
储存分类代码
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
监管及禁止进口产品
此项目有
Xiao Liu et al.
Science China. Life sciences, 63(11), 1744-1754 (2020-05-10)
This study aimed to explore macrophage polarization in acute graft-versus-host disease after hematopoietic stem cell transplantation, and investigated if arsenic trioxide (ATO) could correct this imbalance. In the colon of GVHD mice, we found that the number of F4/80+iNOS+ cells
Cui Li et al.
Toxicology letters, 219(3), 223-230 (2013-04-02)
Arsenic trioxide (As2O3; ATO) is clinically effective in treating acute promyelocytic leukemia (APL); however, it frequently causes cardiotoxic effects. This study was designed to investigate whether ATO could induce apoptosis of cardiac fibroblasts (CFs) that play very important roles in
Ling-Huei Yih et al.
Toxicology and applied pharmacology, 267(3), 228-237 (2013-01-29)
Accumulated evidence has revealed a tight link between arsenic trioxide (ATO)-induced apoptosis and mitotic arrest in cancer cells. AKT, a serine/threonine kinase frequently over-activated in diverse tumors, plays critical roles in stimulating cell cycle progression, abrogating cell cycle checkpoints, suppressing
Athena Kritharis et al.
Annals of hematology, 92(6), 719-730 (2013-03-16)
For more than 2,000 years, arsenic and its derivatives have shown medical utility. Owing to the toxicities and potential carcinogenicity of arsenicals, their popularity has fluctuated. The exact mechanism of action of therapeutic arsenic is not well characterized but likely
Shaohong Fang et al.
Cell death & disease, 12(1), 88-88 (2021-01-20)
Inducing autophagy and inhibiting apoptosis may provide a therapeutic treatment for atherosclerosis (AS). For the treatment of progressive AS, arsenic trioxide (ATO) has been used to coat vascular stents. However, the effect of ATO on autophagy of macrophages is still
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