00189
磺胺二甲嘧啶 溶液
1 mg/mL in H2O
别名:
磺胺二甲基嘧啶 溶液
登录 查看组织和合同定价。
选择尺寸
关于此项目
经验公式（希尔记法）:
C12H14N4O2S
化学文摘社编号:
分子量:
278.33
PubChem Substance ID:
UNSPSC Code:
51283901
Beilstein/REAXYS Number:
261304
MDL number:
SMILES string
Cc1cc(C)nc(NS(=O)(=O)c2ccc(N)cc2)n1
InChI
1S/C12H14N4O2S/c1-8-7-9(2)15-12(14-8)16-19(17,18)11-5-3-10(13)4-6-11/h3-7H,13H2,1-2H3,(H,14,15,16)
InChI key
ASWVTGNCAZCNNR-UHFFFAOYSA-N
form
liquid
concentration
1 mg/mL in H2O
color
colorless
antibiotic activity spectrum
Gram-negative bacteria, Gram-positive bacteria
mode of action
enzyme | inhibits
Quality Level
Application
Sulfadimidine is used to induce cytochrome P450 3A4 (CYP3A4) and to inhibit dihydrofolate reductase (DHFR). It was used to study amantadine acetylation.
Biochem/physiol Actions
Sulfadimidine is a competitive inhibitor of dihydropteroate synthetase to block the synthesis of folic acid. It acts as an inhibitor of dihydrofolate reductase (DHFR).
Packaging
10ML
Other Notes
Conditions for safe storage,including any incompatibilities Keep container tightly closed in a dry and well-ventilated place.Store under inert gas. Light sensitive.
存储类别
12 - Non Combustible Liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves
法规信息
新产品
此项目有
A P Bras et al.
Drug metabolism and disposition: the biological fate of chemicals, 29(5), 676-680 (2001-04-17)
Amantadine acetylation was demonstrated to occur both in vivo and in vitro using transgenic male mice overexpressing spermidine/spermine N(1)-acetyltransferase (SSAT). We previously reported that neither NAT1 nor NAT2 was responsible for catalyzing acetylation of the primary amine group of amantadine.
Gang Luo et al.
Drug metabolism and disposition: the biological fate of chemicals, 30(7), 795-804 (2002-06-18)
Induction of cytochrome P450 3A4 (CYP3A4) is determined typically by employing primary culture of human hepatocytes and measuring CYP3A4 mRNA, protein and microsomal activity. Recently a pregnane X receptor (PXR) reporter gene assay was established to screen CYP3A4 inducers. To
Ma Jesús García-Galán et al.
The Science of the total environment, 409(24), 5505-5512 (2011-09-29)
Degradation of the sulfonamide sulfamethazine (SMZ) by the white-rot fungus Trametes versicolor was assessed. Elimination was achieved to nearly undetectable levels after 20 h in liquid medium when SMZ was added at 9 mg L(-1). Experiments with purified laccase and
Vincent Curtin et al.
Molecular pharmaceutics, 10(1), 386-396 (2012-11-29)
The coprocessing of active pharmaceutical ingredient (API) with an excipient which has a high glass transition temperature (T(g)) is a recognized strategy to stabilize the amorphous form of a drug. This work investigates whether coprocessing a model API, sulfadimidine (SDM)
M Rérat et al.
Preventive veterinary medicine, 103(4), 265-273 (2011-09-29)
The present study was conducted to evaluate the efficacy of two prophylactic antibiotic treatments against bovine respiratory disease (BRD) in veal calves. In addition, the antibiotic susceptibilities of isolated Pasteurellaceae were tested. The calves were treated either on the day
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持