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Merck
CN

04492

Esterase Paenibacillus barcinonensis, recombinant

recombinant, expressed in E. coli, ≥10 U/mg

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化学文摘社编号:
UNSPSC Code:
12352204
EC Number:
232-773-7
NACRES:
NA.54
EC 号:
3.1.1.1
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recombinant

expressed in E. coli

form

crystalline, crystals, powder or flakes

specific activity

≥10 U/mg

storage temp.

−20°C

Application

Esterase Paenibacillus barcinonensis, also known as EstA, may be useful in protein engineering studies. It has been engineered to increase enantioselectivity .

Biochem/physiol Actions

An esterase is a hydrolase that splits esters into acids and alcohols. The esterase catalyzes the transesterification of 1-phenylethanol.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Other Notes

1 U corresponds to the amount of enzyme which converts 1 μmol 4-nitrophenyl-L-acetate per minute at pH 7.5 and 30°C.


pictograms

Health hazard

signalword

Danger

hcodes

Hazard Classifications

Resp. Sens. 1

存储类别

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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分析证书(COA)

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Rational Protein Design of Paenibacillus barcinonensis Esterase EstA for Kinetic Resolution of Tertiary Alcohols
Arnau Bassegoda, et al.
ChemCatChem, 2, 962-967 (2010)
XieMei Tang et al.
Critical reviews in eukaryotic gene expression, 22(3), 179-187 (2012-11-13)
Tuberculosis remains one of the most prevalent and deadly infectious diseases, largely due to the emergence of multidrug-resistant and extensive drug-resistant Mycobacterium tuberculosis, especially the coinfection with HIV. Mycobacterium Ag85 complex (Ag85A, B, and C), with a carboxylesterase consensus sequence
Zhe-Yi Hu et al.
Analytical and bioanalytical chemistry, 405(5), 1695-1704 (2012-12-15)
Dabigatran etexilate (DABE) is an oral prodrug that is rapidly converted by esterases to dabigatran (DAB), a direct inhibitor of thrombin. To elucidate the esterase-mediated metabolic pathway of DABE, a high-performance liquid chromatography/mass spectrometry based metabolite identification and semi-quantitative estimation



全球贸易项目编号

货号GTIN
04492-10MG04061833216958
04492-50MG04061831158113