06372
β-Hydroxypyruvic acid
≥95.0% (dry substance, T)
别名:
3-羟基-2-氧代丙酸
应用
- 总状升麻中的羟基（苯基）丙酮酸还原酶：升麻酸和蜂斗菜酸生物合成中的假定酶。: 本研究考察了β-羟基丙酮酸在总状升麻中生物活性化合物生物合成中的作用，重点介绍了其在植物次生代谢中的重要性及其在药物化学中的潜在应用(Jahn and Petersen, 2024)。
- 肠道微生物群可以保护中枢神经系统免受锰中毒引起的神经退行性变。: 研究表明肠道微生物群产生的β-羟基丙酮酸衍生物可以保护人们免于罹患神经退行性疾病，提供了有关神经系统疾病治疗策略的见解（Wang et al., 2020）。
生化/生理作用
参与光呼吸中碳途径的代谢产物 。
警示用语：
Danger
危险声明
危险分类
Acute Tox. 4 Oral - Skin Corr. 1B
储存分类代码
8A - Combustible corrosive hazardous materials
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
O A Esakova et al.
IUBMB life, 59(2), 104-109 (2007-04-25)
The interaction of thiamine diphosphate (ThDP) with transketolase (TK) involves at least two stages: [formula: see text] During the first stage, an inactive intermediate complex (TK...ThDP) is formed, which is then transformed into a catalytically active holoenzyme (TK* - ThDP).
M Legge
Biochimica et biophysica acta, 1355(2), 99-101 (1997-02-04)
Mouse oocytes and zygotes, when solubilised demonstrated that a range of ketoaldehydes could be utilised as substrates. Of the five ketoaldehydes investigated the overall substrate utilisation was hydroxypyruvate > glyoxylate > 2-ketobutyrate > pyruvate > glycolate. The utilisation of these
M C Lawrence et al.
Journal of molecular biology, 266(2), 381-399 (1997-02-21)
We describe here a sub-family of enzymes related both structurally and functionally to N-acetylneuraminate lyase. Two members of this family (N-acetylneuraminate lyase and dihydrodipicolinate synthase) have known three-dimensional structures and we now proceed to show their structural and functional relationship
William E Karsten et al.
Biochimica et biophysica acta, 1790(6), 575-580 (2009-03-07)
The enzyme L-serine-glyoxylate aminotransferase (SGAT) from Hyphomicrobium methylovorum is a PLP-containing enzyme that catalyzes the conversion of L-serine and glyoxylate to hydroxypyruvate and glycine. The cloned enzyme expressed in Escherichia coli is isolated as a mixture of the E:PLP and
Shweta Joshi et al.
Molecular and biochemical parasitology, 160(1), 32-41 (2008-05-06)
The pentose phosphate pathway (PPP) is an important metabolic pathway for yielding reducing power in the form of NADPH and production of pentose sugar needed for nucleic acid synthesis. Transketolase, the key enzyme of non-oxidative arm of PPP, plays a
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