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Merck
CN

12708

Sigma-Aldrich

Anti-Mouse IgG - Mega 485

别名:

Mega 485-Anti-Mouse-IgG

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MDL编号:
UNSPSC代码:
12352203
NACRES:
NA.46
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生物来源

goat

偶联物

Mega 485 conjugate

抗体形式

affinity isolated antibody

抗体产品类型

primary antibodies

克隆

polyclonal

包含

50% glycerol

种属反应性

mouse

浓度

1 mg/mL protein

荧光

λex 485 nm; λem 552 nm in PBS

储存温度

−20°C

靶向翻译后修饰

unmodified

一般描述

Anti-mouse IgG (whole molecule) is developed in goat using purified mouse IgG as the immunogen. Affinity isolated antigen specific antibody is purified from goat anti-mouse IgG antiserum to remove essentially all goat serum proteins, including immunoglobulins, which do not specifically bind to mouse IgG. The antibody preparation is solid phase adsorbed with human serum proteins to ensure minimal cross reactivity.
Immunoglobulin G (IgG) is a glycoprotein antibody that regulates immune responses such as phagocytosis and is also involved in the development of autoimmune diseases. Mouse IgGs have four distinct isotypes, namely, IgG1, IgG2a, IgG2b, and IgG3. IgG1 regulates complement fixation in mice.
Affinity isolated antigen specific antibody is purified from goat anti-mouse IgG antiserum to remove essentially all goat serum proteins, including immunoglobulins, which do not specifically bind to mouse IgG. The antibody preparation is solid phase adsorbed with human serum proteins to ensure minimal cross reactivity. Hence, Mega 485-goat anti-mouse IgG (whole molecule) is specific for mouse IgG.

免疫原

purified mouse IgG

应用

Mega 485-goat anti-mouse IgG (whole molecule) can be used for fluorescence-based immunoassays.

外形

Mega 485-goat anti-mouse IgG (whole molecule) is provided in unit sizes of 1 ml as 1 mg/ml solutions in 0.1 M sodium phosphate, 0.1 M NaCl, pH 7.5, and has 5 mM sodium azide as a preservative.

分析说明

unconjugated dye ≤5% of total fluorescence

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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储存分类代码

12 - Non Combustible Liquids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves

法规信息

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分析证书(COA)

Lot/Batch Number

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访问文档库

Zaklina Kovacevic et al.
The Journal of biological chemistry, 291(3), 1029-1052 (2015-11-05)
N-MYC downstream-regulated gene-1 (NDRG1) is a potent growth and metastasis suppressor that acts through its inhibitory effects on a wide variety of cellular signaling pathways, including the TGF-β pathway, protein kinase B (AKT)/PI3K pathway, RAS, etc. To investigate the hypothesis
Complement-fixing IgG1 constitutes a new subclass of mouse IgG.
P L Ey et al.
Nature, 281(5731), 492-493 (1979-10-11)
Structure and function of human and murine receptors for IgG.
J C Unkeless et al.
Annual review of immunology, 6, 251-281 (1988-01-01)

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