14520
双(3-氨基丙基)胺
purum, ≥97.0% (GC)
别名:
3,3′-二氨基二丙胺, 3,3′-亚氨基二丙胺, N-(3-氨丙基)-1,3-丙二胺, 二亚丙基三胺, 去甲精眯
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关于此项目
线性分子式:
(NH2CH2CH2CH2)2NH
化学文摘社编号:
分子量:
131.22
EC Number:
200-261-2
UNSPSC Code:
12352100
PubChem Substance ID:
Beilstein/REAXYS Number:
1071254
MDL number:
InChI key
OTBHHUPVCYLGQO-UHFFFAOYSA-N
InChI
1S/C6H17N3/c7-3-1-5-9-6-2-4-8/h9H,1-8H2
SMILES string
NCCCNCCCN
grade
purum
assay
≥97.0% (GC)
refractive index
n20/D 1.481 (lit.), n20/D 1.482
bp
151 °C/50 mmHg (lit.)
mp
−14 °C (lit.)
density
0.938 g/mL at 25 °C (lit.)
Gene Information
mouse ... Odc1(18263)
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signalword
Danger
Hazard Classifications
Acute Tox. 1 Inhalation - Acute Tox. 3 Dermal - Acute Tox. 4 Oral - Muta. 2 - Skin Corr. 1A - Skin Sens. 1A - STOT RE 2
target_organs
thymus
存储类别
6.1B - Non-combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
wgk
WGK 2
flash_point_f
242.6 °F - closed cup
flash_point_c
117 °C - closed cup
ppe
Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
法规信息
新产品
此项目有
Johannes Ghatnekar et al.
Bioorganic & medicinal chemistry, 15(23), 7426-7433 (2007-09-18)
We here report the synthesis of the two polyamine-based nucleoside derivatives 5-{[bis-(3-aminopropyl)amino]acetamido-1-propynyl}uridine and 2-{[bis-(3-aminopropyl)amino]-acetamido-1-propynyl}adenosine. The various polyamine derivatives have been used in thermal melting analysis using DNA from herring testes, and in cellular studies using four different cell lines. The
T Yorifuji et al.
Journal of biochemistry, 122(3), 537-543 (1997-11-05)
Polyamine aminotransferase of Arthrobacter sp. TMP-1 was induced by 1,3-diaminopropane (DAP), N-3-aminopropyl-1,3-diaminopropane (norspermidine), spermidine, and spermine, but not by putrescine. The enzyme was purified to homogeneity. Its molecular weight and subunit size were 129,000 and 64,000, respectively. Its absorption spectrum
T Shinki et al.
European journal of biochemistry, 183(2), 285-290 (1989-08-01)
We have reported that spermidine N1-acetyltransferase has a larger role than ornithine decarboxylase in putrescine synthesis in chick duodenum induced by 1 alpha,25-dihydroxycholecalciferol (calcitriol) [Shinki, T., Kadofuku, T., Sato, T. and Suda, T. (1986) J. Biol. Chem. 261, 11712-11716]. In
Mark J Dixon et al.
Bioorganic & medicinal chemistry, 13(14), 4513-4526 (2005-06-01)
A library of polyamine-peptide conjugates based around some previously identified inhibitors of trypanothione reductase was synthesised by parallel solid-phase chemistry and screened. Kinetic analysis of library members established that subtle structural changes altered their mechanism of action, switching between competitive
E Rowatt et al.
Journal of inorganic biochemistry, 46(2), 87-97 (1992-05-01)
1. The binding of spermine and Mg2+ to DNA has been investigated using the dye arsenazo III to measure unbound cations. 2. The apparent dissociation constant, Kd, of DNA for spermine has been found to be 7.4 +/- 3.9 x
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