biological source
mouse
conjugate
unconjugated
antibody form
culture supernatant
antibody product type
primary antibodies
clone
MB1, monoclonal
description
For In Vitro Diagnostic Use in Select Regions (See Chart)
form
buffered aqueous solution
species reactivity
human
packaging
vial of 0.1 mL concentrate (146M-14), vial of 0.5 mL concentrate (146M-15), bottle of 1.0 mL predilute (146M-17), vial of 1.0 mL concentrate (146M-16), bottle of 7.0 mL predilute (146M-18)
manufacturer/tradename
Cell Marque®
technique(s)
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100
isotype
IgG1
control
tonsil
shipped in
wet ice
storage temp.
2-8°C
visualization
membranous
Gene Information
human ... PTPRC(5788)
General description
MB1 antibody stains preferentially B-cells and their neoplasms but is less specific as it will also react with some T-cell lymphomas and non-lymphoid tumors. The antigen for this antibody is in the membrane of all B-cells with the exception of plasma cells and some mature T-cells.
Physical form
Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide
Preparation Note
Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.
Analysis Note
 IVD |  IVD |  IVD |  RUO |
Other Notes
CD45R Positive Control Slides, Product No. 146S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).
For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com
Legal Information
Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany
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存储类别
12 - Non Combustible Liquids
wgk
WGK 2
法规信息
监管及禁止进口产品
此项目有
S Poppema et al.
The American journal of pathology, 127(3), 418-429 (1987-06-01)
The absence of reactivity on routinely prepared tissue sections has hampered the use of monoclonal antileukocyte antibodies in diagnostic histopathology. Here we describe five new antibodies reactive with leukocyte subsets in formaldehyde-fixed, paraffin-embedded tissue sections. Antibody MT1 is reactive with
A J Norton et al.
Histopathology, 10(12), 1243-1260 (1986-12-01)
Formalin fixed and paraffin wax embedded tissue from 24 cases of T-cell lymphoma diagnosed using immunocytochemistry on cryostat sections was examined using a panel of eight monoclonal and three polyclonal antisera. The monoclonal antibodies UCHL1 and MT1 proved to be
C S Scott et al.
Clinical and experimental immunology, 86(3), 500-505 (1991-12-01)
The differential expression of various membrane CD45R isoforms by normal lymphocyte populations is known to be closely associated with distinct immunoregulatory functions. Abnormal patterns of CD45R expression have been reported in patients with common variable immunodeficiency and HIV infection, and
P S Master et al.
International journal of hematology, 55(3), 235-242 (1992-06-01)
The membrane expression of CD45R isoforms by leukaemic blasts from 92 cases of acute myeloid (AML) and 12 cases of lymphoblastic leukaemia was analysed by single and two-colour flow cytometry. Compared to normal mature granulocytes, which invariably expressed UCHL1 (CD45RO)
S W Chensue et al.
The American journal of pathology, 133(3), 564-572 (1988-12-01)
Using a highly specific rabbit antisera directed against murine tumor necrosis factor (TNF), immunohistochemical localization of this monokine was performed in cultured mouse peritoneal macrophages. Resident macrophages did not express TNF even after stimulus with lipopolysaccharide (LPS). In contrast, 12%
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