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Merck
CN

14825

双(4-氟-3-硝基苯)砜

≥97.0% (HPLC)

别名:

4,4′-二氟-3,3′-二硝基二苯砜, 4-氟-3-硝基苯砜

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关于此项目

线性分子式:
[FC6H3(NO2)]2SO2
化学文摘社编号:
分子量:
344.25
EC Number:
206-224-7
UNSPSC Code:
12352200
PubChem Substance ID:
Beilstein/REAXYS Number:
2486439
MDL number:
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assay

≥97.0% (HPLC)

mp

191-194 °C

SMILES string

[O-][N+](=O)c1cc(ccc1F)S(=O)(=O)c2ccc(F)c(c2)[N+]([O-])=O

InChI

1S/C12H6F2N2O6S/c13-9-3-1-7(5-11(9)15(17)18)23(21,22)8-2-4-10(14)12(6-8)16(19)20/h1-6H

InChI key

KHAWDEWNXJIVCJ-UHFFFAOYSA-N

Application

Bis(4-fluoro-3-nitrophenyl) sulfone has been used to study the high-affinity ATP-binding site on 30S dynein, as well as the staphylococcal protein A in immunoferritin techniques. Bis(4-fluoro-3-nitrophenyl) sulfone has also been used to study ATPase activity and pellet height response of tetrahymena cilia.

Other Notes

Bifunctional reagent for investigating the folding of polypeptide chains; Crosslinking reagent via amino and phenolic hydroxy groups


pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

存储类别

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

法规信息

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Cross-linking of aminotyrosyl residues in the active site of staphylococcal nuclease.
P Cuatrecasas et al.
The Journal of biological chemistry, 244(2), 406-412 (1969-01-25)
F. Wold
Methods in Enzymology, 11, 617-617 (1967)
J J Blum et al.
Journal of supramolecular structure, 11(2), 117-122 (1979-01-01)
The enhancing effect of low concentrations (eg, 8 microM) of bis(4-fluoro-3-nitrophenyl)sulfone (FNS) on 30S dynein ATPase activity is increased when 1 mM dithiothreitol (DTT) is present. The effect of FNS + DTT is optimal at pH 7.5. Activation of the



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货号GTIN
632929-1G04061832721460
632929-5G04061832721477