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Merck
CN

174R-1

Sigma-Aldrich

CD74 (EP167) Rabbit Monoclonal Primary Antibody

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UNSPSC代码:
12352203

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生物来源

rabbit

偶联物

unconjugated

抗体形式

culture supernatant

抗体产品类型

primary antibodies

克隆

EP167, monoclonal

描述

For In Vitro Diagnostic Use in Select Regions

表单

buffered aqueous solution

种属反应性

human

包装

vial of 0.1 mL concentrate (174R-14)
vial of 0.1 mL concentrate Research Use Only (174R-14-RUO)
vial of 0.5 mL concentrate (174R-15)
vial of 1.0 mL concentrate (174R-16)
vial of 1.0 mL concentrate Research Use Only (174R-16-RUO)
vial of 1.0 mL pre-dilute Research Use Only (174R-17-RUO)
vial of 1.0 mL pre-dilute ready-to-use (174R-17)
vial of 7.0 mL pre-dilute ready-to-use (174R-18)
vial of 7.0 mL pre-dilute ready-to-use Research Use Only (174R-18-RUO)

制造商/商品名称

Cell Marque®

技术

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:200 (concentrated)

同位素/亚型

IgG

控制

lymph node, tonsil

运输

wet ice

储存温度

2-8°C

可视化

cytoplasmic, membranous

基因信息

human ... CD74(972)

一般描述

The CD74 antigen represents a membrane-bound subunit of the MHC Class II-associated invariant chain that is encoded by the gene located on Chromosome 5. The antibody recognizes nuclear and cytoplasmic antigens of MW 35 kD and 31 kD respectively. Anti-CD74 stains predominantly germinal center lymphocytes and those in the mantle cell region of the lymph node. It stains the cell membrane but a paranuclear globular labeling is also noted. Plasma cells are not labeled. Thymocytes are negative but dendritic cells are often labeled by anti-CD74. Anti-CD74 labels about 90% of low grade B-cell lymphomas and 20% of low grade T-cell lymphomas. In high-grade lymphomas the discriminatory power (B-cell vs. T-cell) is diminished. Reed-Sternberg cells are also labeled in approximately 60% of cases.1

外形

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.

制备说明

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分析说明


IVD
IVD
IVD
RUO

其他说明

CD74 Positive Control Slides, Product No. 174S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).
For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

法律信息

Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany

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储存分类代码

12 - Non Combustible Liquids

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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分析证书(COA)

Lot/Batch Number

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Manual of Diagnostic Antibodies for Immunohistology (1999)

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