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Merck
CN

17809

Sigma-Aldrich

(-)-肾上腺素 (+)-酒石酸氢盐

tested according to Ph. Eur.

别名:

酒石酸肾上腺素, 酒石酸肾上腺素, 副肾素 (+)-酒石酸氢盐, L-3,4-Dihydroxy-α-(methylaminomethyl)benzyl alcohol D-hydrogen 酒石酸氢盐, L-Adrenaline D-hydrogentartrate

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关于此项目

经验公式（希尔记法）:
C9H13NO3 · C4H6O6
化学文摘社编号:
51-42-3
分子量:
333.29
EC 号:
200-097-1
MDL编号:
MFCD00035077
UNSPSC代码:
12352200
PubChem化学物质编号:
57647680

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Agency

tested according to Ph. Eur.

质量水平

100

溶解性

water: soluble 1 gm in 3 ml
alcohol: slightly soluble
chloroform: insoluble
diethyl ether: insoluble

应用

pharmaceutical (small molecule)

SMILES字符串

O[C@H]([C@@H](O)C(O)=O)C(O)=O.CNC[C@H](O)c1ccc(O)c(O)c1

InChI

1S/C9H13NO3.C4H6O6/c1-10-5-9(13)6-2-3-7(11)8(12)4-6;5-1(3(7)8)2(6)4(9)10/h2-4,9-13H,5H2,1H3;1-2,5-6H,(H,7,8)(H,9,10)/t9-;1-,2-/m01/s1

InChI key

YLXIPWWIOISBDD-NDAAPVSOSA-N

基因信息

human ... ADRA1A(148), ADRA1B(147), ADRA1D(146), ADRA2A(150), ADRA2B(151), ADRA2C(152), ADRB1(153), ADRB2(154), ADRB3(155)

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应用

(-)-Epinephrine (+)-bitartrate salt has been used for studying the active calcium uptake by rainbow trout skin. It has also been used in oxygen-derived oxidant assays for assessing the susceptibility of C. neoformans biofilms to antimicrobial molecules.

生化/生理作用

肾上腺素能受体激动剂。
(-)-Epinephrine (+)-bitartrate salt is an α,β-adrenergic receptor agonist. It inhibits the lipolysis completely and can overcome the antilipolytic impact of insulin in perifused isolated fat cell.

象形图

Skull and crossbones
GHS06

警示用语：

Danger

危险声明

H300

危险分类

Acute Tox. 1 Oral

储存分类代码

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

法规信息

涉药品监管产品
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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
BCBM9979V
BCBK8588V
BCBL3257V
BCBG3894V
BCBD8270V

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W S Marshall et al.
The Journal of experimental biology, 166, 297-316 (1992-05-01)
The skin overlying the cleithrum bone of freshwater-acclimated rainbow trout contains numerous mitochondria-rich (MR) cells, as detected by DASPEI fluorescence. This tissue was mounted in vitro in an Ussing-style chamber with fresh water on the mucosal surface and saline supplemented
S S Solomon et al.
The Journal of laboratory and clinical medicine, 88(6), 984-994 (1976-12-01)
Development of a perifusion system utilizing isolated fat cells (IFC) has converted the static incubation system into one capable of measuring dynamic changes in adipose tissue metabolism. Using this new system, we have studied the initiation by epinephrine and inhibition
Luis R Martinez et al.
Infection and immunity, 74(11), 6118-6123 (2006-10-24)
The human pathogenic fungus Cryptococcus neoformans can form biofilms on polystyrene plates and medical devices in a process that requires capsular polysaccharide release. Although biofilms are known to be less susceptible to antimicrobial drugs, little is known about their susceptibility
Yangjie Wei et al.
AAPS PharmSciTech, 16(2), 455-465 (2014-11-02)
Several attempts have been made to mask the bitter taste of oral formulations, but none have been made for injectable formulations. This study aims to mask the bitter taste of dental lidocaine HCl (LID) injection using hydroxypropyl-β-cyclodextrin (HP-β-CD) and sodium
Margot Van der Jeught et al.
Cellular reprogramming, 17(3), 170-180 (2015-06-09)
In mice, inhibition of both the fibroblast growth factor (FGF) mitogen-activated protein kinase kinase/extracellular-signal regulated kinase (MEK/Erk) and the Wnt signaling inhibitor glycogen synthase-3β (GSK3β) enables the derivation of mouse embryonic stem cells (mESCs) from nonpermissive strains in the presence
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