27555
氯唑西林 钠盐
≥95.0% (HPLC)
别名:
3-(o-Chlorophenyl)-5-methyl-4-isoxazolylpenicillin sodium salt, Syntarpen sodium salt
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关于此项目
经验公式（希尔记法）:
C19H17ClN3NaO5S
化学文摘社编号:
分子量:
457.86
UNSPSC Code:
51102829
NACRES:
NA.85
PubChem Substance ID:
EC Number:
211-390-9
Beilstein/REAXYS Number:
4103180
MDL number:
biological source
semisynthetic
Quality Segment
assay
≥95.0% (HPLC)
form
powder or crystals
impurities
≤5% Total impurities (anhydrous)
color
white to off-white
antibiotic activity spectrum
Gram-positive bacteria
mode of action
cell wall synthesis | interferes
storage temp.
2-8°C
SMILES string
[Na+].Cc1onc(-c2ccccc2Cl)c1C(=O)N[C@H]3[C@H]4SC(C)(C)[C@@H](N4C3=O)C([O-])=O
InChI
1S/C19H18ClN3O5S.Na/c1-8-11(12(22-28-8)9-6-4-5-7-10(9)20)15(24)21-13-16(25)23-14(18(26)27)19(2,3)29-17(13)23;/h4-7,13-14,17H,1-3H3,(H,21,24)(H,26,27);/q;+1/p-1/t13-,14+,17-;/m1./s1
InChI key
SCLZRKVZRBKZCR-SLINCCQESA-M
General description
Chemical structure: β-lactam
Application
Cloxacillin is a semisynthetic antibiotic in the same class as penicillin. Cloxacillin is used against staphylococci that produce β-lactamase. It is used to study the role of pH in antibiotic effectiveness and how oxgall, acid, and hydrogen peroxide stress effects the susceptibility of Bifidobacteria.
Biochem/physiol Actions
Cloxacillin interferes with the last stage of bacterial cell wall synthesis by binding to penicillin-binding proteins. This inhibits the necessary cross-linking and leads to autolysis of the bacteria by autolysins.
Other Notes
Keep container tightly closed in a dry and well-ventilated place.
存储类别
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 645583-10G | 04061831830804 |
| 27555-1G-F | 04061826168332 |
| 27555-5G-F | 04061826168387 |