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Merck
CN

30396

细胞色素 C 来源于马心脏

≥90% (GE)

别名:

Cytochrome c 来源于马心脏

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化学文摘社编号:
UNSPSC Code:
12352202
EC Number:
232-700-9
MDL number:
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biological source

horse heart

assay

≥90% (GE)

form

powder or flakes

mol wt

Mr ~13000

impurities

≤10% water, ≤5% cytochrome c reduced

solubility

H2O: 10 mg/mL, clear, dark red-brown

UniProt accession no.

storage temp.

−20°C

Gene Information

horse ... CYCS(100053958)

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Application

马的细胞色素c经过H2O2和UV 处理后的特异性位点和氧化程度已经过表征。研究表明这些位点可能可用作细胞内氧化环境的生物标记。

Biochem/physiol Actions

细胞色素c的主要身份是电子载体线粒体蛋白。在细胞内,细胞色素c能够在二价铁和三价铁之间转化,使得它称为了有效的生物电子载体,在动植物细胞内氧化中起到很重要的作用。它通常被视作呼吸作用催化剂,在呼吸底物和氧气之间形成必需的电子桥

Preparation Note

By a procedure which completely avoids TCA and gives a highly native form.

Other Notes

Sales restrictions may apply

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

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Andrew E Maclean et al.
Current biology : CB, 28(10), 1614-1619 (2018-05-08)
Parasitism is a life history strategy found across all domains of life whereby nutrition is obtained from a host. It is often associated with reductive evolution of the genome, including loss of genes from the organellar genomes [1, 2]. In
Alexander N Volkov et al.
Biochemistry, 52(13), 2165-2175 (2013-03-23)
Here we present the preparation, biophysical characterization, and nuclear magnetic resonance (NMR) spectroscopy study of yeast cytochrome c peroxidase (CcP) constructs with enhanced solubility. Using a high-yield Escherichia coli expression system, we routinely produced uniformly labeled [(2)H,(13)C,(15)N]CcP samples with high
Chris L Bergstrom et al.
Proceedings of the National Academy of Sciences of the United States of America, 110(16), 6269-6274 (2013-04-12)
The release of cytochrome c from mitochondria is a key signaling mechanism in apoptosis. Although extramitochondrial proteins are thought to initiate this release, the exact mechanisms remain unclear. Cytochrome c (cyt c) binds to and penetrates lipid structures containing the
Margareta R A Blomberg et al.
Biochimica et biophysica acta, 1827(7), 826-833 (2013-04-27)
The membrane-bound enzyme cNOR (cytochrome c dependent nitric oxide reductase) catalyzes the reduction of NO in a non-electrogenic process. This is in contrast to the reduction of O2 in cytochrome c oxidase (CcO), the other member of the heme-copper oxidase
Rawabi Qadhi et al.
Toxicology letters, 219(3), 288-297 (2013-03-26)
The importance of dietary polyunsaturated fatty acids (PUFAs) in the reduction of cardiovascular disease has been recognized for many years. Docosahexaenoic acid (22:6n3, DHA) is an n-3 PUFA known to affect numerous biological functions and provide cardioprotection; however, the exact

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