30927
2′-脱氧腺苷-5′-三磷酸 二钠盐
≥90% (HPLC)
别名:
数据-Na 2
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关于此项目
经验公式（希尔记法）:
C10H14N5Na2O12P3
化学文摘社编号:
分子量:
535.15
UNSPSC Code:
41106305
PubChem Substance ID:
EC Number:
277-809-2
MDL number:
eCl@ss:
32160414
assay
≥90% (HPLC)
storage temp.
−20°C
SMILES string
[Na+].[Na+].Nc1ncnc2n(cnc12)C3C[C@H](O)[C@@H](COP(O)(=O)OP([O-])(=O)OP(O)([O-])=O)O3
InChI
1S/C10H16N5O12P3.2Na/c11-9-8-10(13-3-12-9)15(4-14-8)7-1-5(16)6(25-7)2-24-29(20,21)27-30(22,23)26-28(17,18)19;;/h3-7,16H,1-2H2,(H,20,21)(H,22,23)(H2,11,12,13)(H2,17,18,19);;/q;2*+1/p-2/t5-,6+,7?;;/m0../s1
InChI key
JEKDCIBJADJZSK-LNUHRGGJSA-L
Application
2′-Deoxyadenosine 5′-triphosphate (dATP) is used as a substrate by a variety of polymerases including DNA polymerase(s) and reverse transcriptase(s).
Other Notes
Substrate for DNA polymers for studying the mechanism of DNA replication
存储类别
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Jennifer N Patro et al.
Biochemistry, 48(1), 180-189 (2008-12-17)
We used a series of dNTP analogues in conjunction with templates containing modified bases to elucidate the role that N(2) of a purine plays during dNTP polymerization by human DNA polymerase alpha. Removing N(2) from dGTP had small effects during
Fadia Haddad et al.
Methods in molecular biology (Clifton, N.J.), 630, 261-270 (2010-03-20)
Reverse transcription (RT) is the synthesis of complementary deoxyribonucleic acids (DNA) from single-stranded ribonucleic acid (RNA) templates. This process is catalyzed by the reverse transcriptase enzyme, which is the replicating enzyme of retroviruses. Reverse transcriptase was discovered in 1970, and
Michael Trostler et al.
Biochemistry, 48(21), 4633-4641 (2009-04-08)
We used a series of dATP and dGTP analogues to determine how DNA polymerase I from Bacillus stearothermophilus (BF), a prototypical A family polymerase, uses N-1, N(2), N-3, and N(6) of purine dNTPs to differentiate between right and wrong nucleotide