317M-1
Cytokeratin 17 (Ks 17.E3) Mouse Monoclonal Antibody
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关于此项目
NACRES:
NA.41
UNSPSC Code:
12352202
Conjugate:
unconjugated
Clone:
Ks 17.E3, monoclonal
Application:
IHC (p)
Citations:
4
biological source
mouse
conjugate
unconjugated
antibody form
diluted ascites fluid
antibody product type
primary antibodies
clone
Ks 17.E3, monoclonal
description
For In Vitro Diagnostic Use in Select Regions (See Chart)
form
buffered aqueous solution
species reactivity
human
packaging
vial of 0.1 mL concentrate (317M-14), vial of 0.5 mL concentrate (317M-15), bottle of 1.0 mL predilute (317M-17), vial of 1.0 mL concentrate (317M-16), bottle of 7.0 mL predilute (317M-18)
manufacturer/tradename
Cell Marque®
technique(s)
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100
isotype
IgG2b
control
cervix neoplasia III
shipped in
wet ice
storage temp.
2-8°C
visualization
cytoplasmic
Gene Information
human ... KRT17(3872)
General description
Cytokeratin 17 is 46 kD intermediate filament found in simple epithelia sometimes in association with Cytokeratin 7. This antibody has been used to distinguish cervical immature squamous metaplasia from high grade cervical intraepithelial neoplasia (CIN III). Anti-CK 17 also labels myoepithelial cells in the benign breast tissue. CK 17 labelling of breast carcinoma cells (so-called basal phenotype) has been associated with a poor prognosis.
Physical form
Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide
Preparation Note
Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.
Analysis Note
 IVD |  IVD |  IVD |  RUO |
Other Notes
Cytokeratin 17 Positive Control Slides , Product No. 317S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).
For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com
Legal Information
Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany
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此项目有
S Regauer et al.
Histopathology, 50(5), 629-635 (2007-03-31)
Atypical immature metaplasia (AIM) refers to a full-thickness intraepithelial basaloid lesion in the uterine cervix that features both metaplasia and atypia and is therefore difficult to distinguish from high-grade cervical intraepithelial neoplasia (CIN III). p16 is a marker for human
Jolise E Martens et al.
Anticancer research, 24(2B), 771-775 (2004-05-27)
Basic research on HPV has focused on identifying the genetic changes that lead to cervical carcinoma. However, while focusing on the molecular biology of the cancer, understanding of its cellular biology has lagged: the target cell of the HPV infection
Peiguo G Chu et al.
The American journal of surgical pathology, 29(3), 359-367 (2005-02-24)
Pancreatobiliary and ampulla of Vater adenocarcinomas frequently metastasize to regional lymph nodes, liver, or lung and are difficult to diagnose because they lack specific immunohistochemical markers. We studied the expression of cytokeratin 7 (CK7), cytokeratin 17 (CK17), cytokeratin 20 (CK20)
Raanan Cohen-Kerem et al.
The Annals of otology, rhinology, and laryngology, 113(10), 821-827 (2004-11-13)
To assess cytokeratin-17 (CK17) as an immunohistochemical marker for squamous cell carcinoma of the larynx, we stained 63 tissue samples from 63 consecutive patients who were believed or suspected to have squamous cell carcinoma of the larynx for CK17 and
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