33440
D -甘露醇
puriss. p.a., ≥98% (calc. to the dried substance, HPLC)
别名:
甘露糖醇
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经验公式（希尔记法）:
C6H14O6
化学文摘社编号:
分子量:
182.17
EC Number:
200-711-8
UNSPSC Code:
12352201
PubChem Substance ID:
Beilstein/REAXYS Number:
1721898
MDL number:
InChI key
FBPFZTCFMRRESA-KVTDHHQDSA-N
InChI
1S/C6H14O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3-12H,1-2H2/t3-,4-,5-,6-/m1/s1
SMILES string
OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO
grade
puriss. p.a.
assay
≥98% (calc. to the dried substance, HPLC)
optical activity
[α]20/D +23 to +25°, c = 8% in Na2B4O7
impurities
reducing sugars, complies, ≤0.0072% free acid (as CH3COOH), ≤0.3% water (Karl Fischer)
ign. residue
≤0.05% (as SO4)
mp
165-168 °C, 167-170 °C (lit.)
anion traces
chloride (Cl-): ≤50 mg/kg, sulfate (SO42-): ≤100 mg/kg
cation traces
As: ≤1 mg/kg, Ca: ≤10 mg/kg, Cu: ≤5 mg/kg, Fe: ≤10 mg/kg, Ni: ≤1 mg/kg, Pb: ≤1 mg/kg, Zn: ≤5 mg/kg
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Biochem/physiol Actions
一种糖醇类甜味剂。 用于甜味抑制研究。
存储类别
11 - Combustible Solids
wgk
WGK 1
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
新产品
此项目有
Maria Badal Tejedor et al.
International journal of pharmaceutics, 486(1-2), 315-323 (2015-04-07)
Tablets are the most convenient form for drug administration. However, despite the ease of manufacturing problems such as powder adhesion occur during the production process. This study presents surface and structural characterization of tablets formulated with commonly used excipients (microcrystalline
Heikki O Koskela et al.
Chest, 124(6), 2171-2177 (2003-12-11)
To compare a new bronchial provocation test, the mannitol challenge, with cold air and histamine challenges to demonstrate airway hyperresponsiveness (AHR) in patients with difficult-to-diagnose asthma. A prospective study. Thirty-seven consecutive patients with recently diagnosed, steroid-naive, mild, or atypical asthma
Heikki O Koskela et al.
Chest, 124(4), 1341-1349 (2003-10-14)
To compare the sensitivity and validity of mannitol, histamine, and cold air challenges to demonstrate the effect of inhaled corticosteroids (ICS) in asthma. A prospective study. Seventeen patients with recently diagnosed, steroid-naive asthma who fulfilled the diagnostic criteria of Finnish
Heikki O Koskela et al.
Chest, 125(6), 1985-1992 (2004-06-11)
To define whether coughing during mannitol challenge is a nonspecific side effect of this challenge or is associated with asthma. A prospective study. University hospital. Thirty-seven steroid-naive, asthmatic subjects and 10 healthy subjects. The participants completed a symptom questionnaire, recorded
Diana Bilton et al.
Thorax, 69(12), 1073-1079 (2014-09-24)
Bronchiectasis is characterised by excessive production of mucus and pulmonary exacerbations. Inhaled osmotic agents may enhance mucociliary clearance, but few long-term clinical trials have been conducted. To determine the impact of inhaled mannitol on exacerbation rates in patients with non-cystic
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