Cultrex^™ 3-D Spheroid Cell Invasion Assay

The need for more complete and physiologically predictive cancer invasion models has driven the development of the 3-D Culture 96 Well BME Cell Invasion Assay. There is growing evidence that tumor cell aggregates or spheroids are more representative of tumors in vivo, and they exhibit several physiological traits including similar morphology, the formation of cell-cell bonds, decreased proliferation rates, increased cell survival, tumor dormancy, and a hypoxic core. Applying this model to in a 3-D culture invasion assay provides a more physiological approach for assessing tumor invasion and providing a visual component that can be quantitated through image analysis.

Storage Conditions and Product Stability:
Components are stored at room temperature and -80°C. Strip seals are provided to preserve sterility of unused wells from the 96 Well, round bottom plate for subsequent experiments.

6538 is a trademark of American Type Culture Collection