37970
5,7-Dihydroxytryptamine creatinine sulfate salt
≥97.0% (HPLC)
别名:
5,7-DHT, 7-Hydroxyserotonin creatinine sulfate salt
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关于此项目
经验公式（希尔记法）:
C10H12N2O2 · C4H7N3O · H2SO4
化学文摘社编号:
分子量:
403.41
PubChem Substance ID:
UNSPSC Code:
12352200
Beilstein/REAXYS Number:
8817524
MDL number:
assay
≥97.0% (HPLC)
shipped in
wet ice
storage temp.
−20°C
SMILES string
OS(O)(=O)=O.CN1CC(=O)N=C1N.NCCc2c[nH]c3c(O)cc(O)cc23
InChI
1S/C10H12N2O2.C4H7N3O.H2O4S/c11-2-1-6-5-12-10-8(6)3-7(13)4-9(10)14;1-7-2-3(8)6-4(7)5;1-5(2,3)4/h3-5,12-14H,1-2,11H2;2H2,1H3,(H2,5,6,8);(H2,1,2,3,4)
InChI key
BXYXUOWJXUUTQZ-UHFFFAOYSA-N
Biochem/physiol Actions
Neurotoxin that is relatively selective for serotonergic terminals in adults and gives long-lasting destruction of serotonergic neurons when given neonatally; adrenergic neurotoxicity can be blocked by pretreating with desipramine.
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
法规信息
新产品
此项目有
Hai Lin et al.
Neuroscience letters, 598, 91-95 (2015-05-20)
Although tianeptine, an atypical antidepressant has been reported to have antinociceptive effects, the mode of action is different from that of tricyclic antidepressants despite structural similarities. We examined the antiallodynic effect of intrathecal tianeptine in neuropathic pain rats and determined
Victoria M Smith et al.
The European journal of neuroscience, 42(10), 2805-2817 (2015-10-13)
Light serves as the primary stimulus that synchronizes the circadian clock in the suprachiasmatic nucleus (SCN) to the external day/night cycle. Appropriately timed light exposure can reset the phase of the circadian clock. Some serotonergic drugs that bind to the
Lining Cao et al.
Frontiers in cellular neuroscience, 11, 131-131 (2017-05-24)
In the brain, the serotonergic neurons located in the raphe nucleus are the unique resource of the neurotransmitter serotonin, which plays a pivotal role in the regulation of brain development and functions. Dysfunction of the serotonin system is present in
Tatsunori Tanaka et al.
The international journal of neuropsychopharmacology, 20(5), 410-421 (2016-12-31)
Isolation-reared mice show social encounter-induced hyperactivity with activation of prefrontal serotonergic and dopaminergic systems, but it is not known whether this stress response is observed in other pathological conditions. Here we examined whether the social encounter stimulation induces abnormal behavior
Jun-Qi Yao et al.
Neuropharmacology, 178, 108230-108230 (2020-07-22)
Anxiety disorders are the most prevalent group of mental disorders globally, leading to considerable losses in health, functioning and increase of medical costs. Till now, the search for novel pharmacological treatments is driven by the growing medical need to improve
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