39197
N-Dansylethylenediamine
suitable for fluorescence
别名:
N-(2-Aminoethyl)-5-dimethylamino-1-naphthalenesulfonamide, N-(2-Aminoethyl)dansylamide, DNSEDA, NSC 666752
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关于此项目
经验公式（希尔记法）:
C14H19N3O2S
化学文摘社编号:
分子量:
293.38
UNSPSC Code:
12352202
NACRES:
NA.32
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
2817535
产品名称
N-Dansylethylenediamine, suitable for fluorescence
InChI
1S/C14H19N3O2S/c1-17(2)13-7-3-6-12-11(13)5-4-8-14(12)20(18,19)16-10-9-15/h3-8,16H,9-10,15H2,1-2H3
InChI key
CSJXLKVNKAXFSI-UHFFFAOYSA-N
SMILES string
CN(C)c1cccc2c(cccc12)S(=O)(=O)NCCN
assay
≥90% (TLC)
solubility
methanol: 1 mg/mL, clear, slightly yellow to deep yellow
fluorescence
λex 360 nm; λem 530 nm±10 nm in methanol
suitability
suitable for fluorescence
storage temp.
−20°C
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signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
E Kim et al.
Biophysical journal, 70(3), 1439-1446 (1996-03-01)
Actin labeled at Gln-41 with dansyl ethylenediamine (DED) via transglutaminase reaction was used for monitoring the interaction of myosin subfragment 1 (S1) with the His-40-Gly-42 site in the 38-52 loop on F-actin. Proteolytic digestions of F-actin with subtilisin and trypsin
E Kim et al.
Biophysical journal, 69(5), 2024-2032 (1995-11-01)
Gln-41 on G-actin was specifically labeled with a fluorescent probe, dansyl ethylenediamine (DED), via transglutaminase reaction to explore the conformational changes in subdomain 2 of actin. Replacement of Ca2+ with Mg2+ and ATP with ADP on G-actin produced large changes
Emma L Doyle et al.
Journal of the American Chemical Society, 125(15), 4593-4599 (2003-04-10)
The binding of copper(II) ions to membrane-bound synthetic receptors has been investigated. Complexation fitted a 4:1 receptor:copper(II) model, and the observed binding constants are significantly enhanced at the membrane relative to solution; these effects can be explained by the lower
J Moraczewska et al.
Biophysical journal, 77(1), 373-385 (1999-07-02)
Conformational changes in subdomain 2 of actin were investigated using fluorescence probes dansyl cadaverine (DC) or dansyl ethylenediamine (DED) covalently attached to Gln41. Examination of changes in the fluorescence emission spectra as a function of time during Ca2+/Mg2+ and ATP/ADP
Edna Blotnick et al.
BMC biochemistry, 18(1), 3-3 (2017-03-08)
Histatins are histidine rich polypeptides produced in the parotid and submandibular gland and secreted into the saliva. Histatin-3 and -5 are the most important polycationic histatins. They possess antimicrobial activity against fungi such as Candida albicans. Histatin-5 has a higher
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