39197
N-Dansylethylenediamine
suitable for fluorescence
别名:
N-(2-Aminoethyl)-5-dimethylamino-1-naphthalenesulfonamide, N-(2-Aminoethyl)dansylamide, DNSEDA, NSC 666752
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关于此项目
经验公式（希尔记法）:
C14H19N3O2S
化学文摘社编号:
分子量:
293.38
UNSPSC Code:
12352202
NACRES:
NA.32
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
2817535
InChI
1S/C14H19N3O2S/c1-17(2)13-7-3-6-12-11(13)5-4-8-14(12)20(18,19)16-10-9-15/h3-8,16H,9-10,15H2,1-2H3
InChI key
CSJXLKVNKAXFSI-UHFFFAOYSA-N
SMILES string
CN(C)c1cccc2c(cccc12)S(=O)(=O)NCCN
assay
≥90% (TLC)
solubility
methanol: 1 mg/mL, clear, slightly yellow to deep yellow
fluorescence
λex 360 nm; λem 530 nm±10 nm in methanol
suitability
suitable for fluorescence
storage temp.
−20°C
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signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
E Kim et al.
Biophysical journal, 69(5), 2024-2032 (1995-11-01)
Gln-41 on G-actin was specifically labeled with a fluorescent probe, dansyl ethylenediamine (DED), via transglutaminase reaction to explore the conformational changes in subdomain 2 of actin. Replacement of Ca2+ with Mg2+ and ATP with ADP on G-actin produced large changes
E Kim et al.
Biophysical journal, 70(3), 1439-1446 (1996-03-01)
Actin labeled at Gln-41 with dansyl ethylenediamine (DED) via transglutaminase reaction was used for monitoring the interaction of myosin subfragment 1 (S1) with the His-40-Gly-42 site in the 38-52 loop on F-actin. Proteolytic digestions of F-actin with subtilisin and trypsin
Emma L Doyle et al.
Journal of the American Chemical Society, 125(15), 4593-4599 (2003-04-10)
The binding of copper(II) ions to membrane-bound synthetic receptors has been investigated. Complexation fitted a 4:1 receptor:copper(II) model, and the observed binding constants are significantly enhanced at the membrane relative to solution; these effects can be explained by the lower
Xiaolan Yang et al.
BMC biotechnology, 11, 44-44 (2011-05-07)
The combinatorial library strategy of using multiple candidate ligands in mixtures as library members is ideal in terms of cost and efficiency, but needs special screening methods to estimate the affinities of candidate ligands in such mixtures. Herein, a new
D H Atha et al.
Biochimica et biophysica acta, 785(1-2), 1-6 (1984-02-28)
Derivatives of human thrombin and antithrombin III with fluorescent labels covalently attached to their carbohydrate moieties were prepared by reaction of periodate-oxidized proteins with amino derivatives of dansyl, fluorescein and pyrene. The labeled derivatives retained full biological activity, including their
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